Impact of health information technology on detection of potential adverse drug events at the ordering stage

Abstract

The implementation of CPOE and advanced CDSS tools significantly increased the number of potential ADE alerts for pharmacist review and the number of true-positive ADE alerts identified per 1000 admissions.

Impacts and Risks of Adopting Clinical Decision Support Systems

“…Mahoney et al (2007) found that the use of integrated clinical information system technology "decreased selected types of medication errors throughout the medication-use process in a health care system and improved therapeutic drug monitoring in patients" (p. 1969). In the context of identifying the potential adverse drug events (ADEs) at the medication ordering stage, Roberts et al (2010) noted that successful implementation of CPOE and other advanced CDSS tools "significantly increased the number of potential ADE alerts for pharmacist review and the number of true-positive ADE alerts identified per 1000 admissions" (p. 1845). Moreover, in a randomized control trial conducted to evaluate the effectiveness of CDSS in reducing potentially inappropriate prescribing to older adults, Terrell et al (2009) found that CPOE with decision support "significantly reduced prescribing of potentially inappropriate medications for seniors" (p. 1389).…”

“…The knowledge base depends on a centralized clinical data repository (K. Kawamoto, Lobach, Willard, & Ginsburg, 2009;Roberts et al, 2010). The fact that CDSS depends on good quality clinical data repository reinforces the need for standardized data representation, storage, and retrieval that can be centrally managed in the knowledge base repositories.…”

Medication safety and knowledge‐based functions: a stepwise approach against information overload

“…Clinical decision support systems (CDSSs) have been repeatedly advocated to prevent drug therapy problems . A multitude of commercial drug information systems such as Black‐BoxRx, Drugdex, Epocrates, Facts and Comparisons, Lexicomp, PDF.NET are available internationally as well as from German vendors (e.g.…”

Gestion des interactions médicamenteuses par le pharmacien hospitalier : enquête sur les outils documentaires employés et expression du ressenti

“…L'intervention sera d'autant plus pertinente qu'elle sera concise et dépourvue d'ambiguïté [11]. Pour contribuer à cette action, le pharmacien [14]. Sans ce tri préalable, une revue des données de la littérature montre que les médecins outrepassent 49% à 96% des alertes selon les études [15].…”