Impact of Excessive Weight Loss on Cardiovascular Risk After Two Years of Bariatric Surgery

Abstract

Overweightness is related to a high incidence of dyslipidemia, being considered a risk factor for cardiovascular diseases.Objective: Analysis of the effect of weight loss in reducing type 2 diabetes mellitus and cardiovascular risk 2 years after Roux-en-Y gastric bypass.Methods: A retrospective study with patients who underwent Roux-en-Y gastric bypass involving accessing the database of an Obesity Surgery Clinic from March 2018 to March 2019. Male and female patients, aged 18 and over, who underwent bariatric surgery from March 2014 to March 2016 were analyzed. The following data were obtained from the medical records of patients: body weight, height, age, sex, glucose and glycated hemoglobin (HbA1C) after 24 months of surgery.Results: In total, 351 patients were studied, 80.9% of whom were female. There was a reduction in weight and in the concentrations of all biochemical parameters, except HDLc, along with a decrease in the frequency of dyslipidemia and cardiovascular risk 24 months after surgery. When comparing variations between 6 and 12 months, only group 1 reduced Hb1Ac and decreased CVR. There was a significant reduction in the level of glucose in group 1 (p = 0.036) at T4 (18 months) and T5 (24 months).Conclusion: The positive impact determined by bariatric surgery on weight loss was shown to be effective in improving the dyslipidemic profile, reducing morbidities associated with obesity and, consequently, reducing CVR after 24 months.

Redução do Risco Cardiovascular de Framingham em pacientes obesos submetidos a Gastrectomia Vertical (Sleeve) e Gastroplastia em Y-de-roux (Bypass gástrico) em uma instituição privada

“…A redução relativa foi de 26% para ambos procedimentos, o que é compatível com estudos similares na literatura. Esse dado é importante, já que estudos similares, há uma discreta vantagem do bypass sobre o Sleeve, e no atual o sleeve mostrou-se equiparável tanto na redução de comorbidades quanto do RCF (Aronne et al, 2007;Gutierrez-Blanco et al, 2017;Pedron et al, 2021). Porém, segundo tais estudos, a comparação entre ambos os tipos de cirurgia e a redução do RCF é difícil devido à multifatoriedade em relação ao estudo da amostra.…”

“…Porém, segundo tais estudos, a comparação entre ambos os tipos de cirurgia e a redução do RCF é difícil devido à multifatoriedade em relação ao estudo da amostra. Percebe-se então que independente do procedimento, há um significativo impacto positivo da cirurgia bariátrica na diminuição da morbimortalidade desses pacientes (Heneghan et al, 2011;Milla et al, 2020;Pedron et al, 2021).…”