Impact of Entamoeba histolytica on the human body

Abstract

Background: Entamoeba histolytica is a unicellular, protozoon parasite of humans. It moves by a jelly-like tongue-like protrusion of the cytoplasm “pseudopodium”. Infections by this parasite lead to distinct clinical manifestations, including diarrhea, mild abdominal pain, loss of appetite, fatigue, dysentery, and hepatic liver abscess. Methods: In this paper, we discussed about Entamoeba histolytica disease, its epidemiology, pathophysiology, hygiene, causes, risk factors, clinical manifestation and complications, method of transmission, diagnosis, treatment, and incubation period in human body. Results: It is the second leading cause of death. It was diagnosed by taking a complete history and testing stool samples for the presence of E. histolytica cysts. It was treated pharmacologically and surgically. Conclusion: We have concluded that the Entamoeba histolytica is an infection mostly related to fecal-oral transmission due to poor hand hygiene, defecation into water sources such as rivers, and being near animals, and gay or bisexual males due to the risk of fecal-oral contamination through oral and anal sex. It is the second leading cause of death from parasitic intestinal disease worldwide. Key Words: Entamoeba histolytica, epidemiology, pathophysiology, hygiene, incubation period, human body

Efficacy of Paromomycin-Conjugated Nano Chitosan in Treating Entamoeba histolytica Infection in Mice

“…The parasite Entamoeba histolytica is a unicellular protozoon that causes Intestinal amebiasis with an estimated infection of 40,000 -100,000 deaths worldwide annually and spreads up to 10% of the world's population (Sabeeh et al, 2022;Jasni et al, 2022). It has a global impact, especially in the tropics and subtropics (Shirley et al, 2018) The life cycle of E. histolytica is simple and depends on trophozoite (vegetative stage) and cyst (infective stage), Amebiasis infections are typically transmitted by fecal-oral transmission as the infection occurs after consuming food and drinks contaminated with cysts, particularly in areas with inadequate hand hygiene standards (Sharif and Mohammed, 2022). After the ingestion of the parasitic cyst, the excystation occurs in the small intestine, motile Significance | Entamoeba histolytica causes widespread amebiasis.…”