Impact of Early Incorporation of Nutrition Interventions as a Component of Cancer Therapy in Adults: A Review

Richards, Julie; Arensberg, Mary Beth; Thomas, Sara; Kerr, Kirk W.; Hegazi, Refaat; Bastasch, Michael D.

doi:10.3390/nu12113403

Cited by 28 publications

(26 citation statements)

References 48 publications

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“…Mounting insight into cancer metabolism and treatment is also underlining the importance of diet and specific nutrients in both limiting drug-induced side effects and tumor therapeutic response ( 21 , 22 ). Nonetheless, considering the high heterogeneity of the different kind of cancers, there is still much to be learned before being able to develop evidence-based tailored nutritional interventions for all the existing tumor treatment options ( 23 , 24 ).…”

Section: Introductionmentioning

confidence: 99%

Results of the ECHO (Eating habits CHanges in Oncologic patients) Survey: An Italian Cross-Sectional Multicentric Study to Explore Dietary Changes and Dietary Supplement Use, in Breast Cancer Survivors

et al. 2021

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The role of a healthy diet in cancer prevention is well recognized. Recent data indicate that following the same advices can also improve cancer survivors’ quality of life. Breast cancer (BC) patients are commonly concerned about diet and nutrition and frequently express the need to obtain health-related information and the will to change their diet and lifestyle. Hence, be aware of survivors’ dietary changes and information needs is crucial for healthcare professionals to guide them toward optimal lifestyle choices. In order to investigate eating habits changes in a BC survivors’ population, we conceived the cross-sectional multicentric study ECHO (Eating habits CHanges in Oncologic patients) Survey. Data were collected from 684 patients, diagnosed with invasive breast cancer, in order to investigate their changes in food consumption, use of supplements, or the beginning of a specific diet, after BC diagnosis. We also examined the sources of information used and if any modification in their diets was reported to the oncologist. We primarily observed that patients increased their consumption of vegetables, pulses, nuts, fruits, wholemeal bread/pasta, grains and fish; while decreasing red and processed meat, refined bread/pasta, baked good and animal fat consumption. Survivors also reported the use of dietary supplements, mainly vitamins, aimed at counteracting therapies’ side effects. Changes in nutritional habits were often adopted without asking or informing the oncologist. Despite BC survivors made some positive changes in their nutritional habits, those modifications were mostly pursued by less than half of them, while the majority of patients consumed nutritional supplements after diagnosis. These results, as well as the failure to communicate with the physicians, reinforce the need to both improve the patient-healthcare professional relationship and to develop tailored nutrition counselling and intervention programs for cancer survivors.

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Section: Introductionmentioning

confidence: 99%

Results of the ECHO (Eating habits CHanges in Oncologic patients) Survey: An Italian Cross-Sectional Multicentric Study to Explore Dietary Changes and Dietary Supplement Use, in Breast Cancer Survivors

et al. 2021

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“…Defensive micronutrients, carcinogens and mutagens may adapt cancer development in genetically susceptible individuals (Patel et al, 2018). Early nutritional intervention improves health status in cancer patients (Richards et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

Tumorigenic Potential of Dimethyl Sulfoxide, Anthracene in Fish and Anthracene in Dimethyl Sulfoxide in Rattus Norvegicus

Johnson

Saganuwan

Onyeyili

2021

Preprint

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Anthracene is a polyaromatic hydrocarbon (PAH), present in cigarette smoke and some industries. It may cause tumorigenesis of lungs and other organs. Randomized controlled trial was adopted for the study. Seven out of forty-three rats were used for determination of median lethal dose (LD50), whereas thirty-six (36) rats were divided into six groups of six per group. The first group was treated daily with3ml/kg body weight ofwater; the second was treated daily withdimethyl sulfoxide (DMSO) (30mg/kg), whereas third, fourth and fifth groups were treated with anthracene in DMSO at12.5, 25 and 50 mg/kg body weight, respectively.The sixth group was treated daily withanthracene in fish (75 mg/kg)for a period of three weeks. Pre-treatment blood samples were collected on day zero (0) and thereafter on day 7, 14 and 21 respectively for haematological, cardiorespiratory, tumour kinetic, allometric parameters, as as well as oncogenic biomarkers. Findings revealed that dimethyl sufoxide and anthracene may cause adenocarcinoma of lung characterised by anaemia, neutrophilia or neutropenia, increased cancer antigen-125 (CA-125), carcinoembryonic antigen (CEA), increased heart rate and respiratory rate, superior vena cava oedema and histological changes such as reduced alveolar space, damaged alveolar sacs and infiltration of interseptal space with mononuclear cells. Micro nodules were observed in fibrosed lungs. Hence there is need to assess hazard risk of anthracene in industries and anthracene contaminated environment.

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“…One of the most common questions of cancer patients and caregivers is "what should I eat or drink to improve my situation?" [58] This topic is very important but sometimes relatively neglected because of many time-consuming tasks associated with accurately prescribing chemotherapeutics and radiation therapy accurately and on time [58][59][60][61][62][63][64][65]. Fortunately, dietitians with oncology experience can provide tools and information to patients regarding food choices, eating behavior, and issues including poor oral intake and intermittent fasting when patients get chemotherapy and/or radiation [66][67][68].…”

Section: Review Of Strategies To Improve Eating Behaviors While Receiving Chemotherapy And/or Radiationmentioning

confidence: 99%

“…Malnutrition in cancer patients is a common problem. There are many indices and tools to define malnutrition, cachexia, and sarcopenia [35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51]62,[69][70][71][72][73][74][75][76][77]. Although weight loss from the time of diagnosis is one measure, the quantity and quality of food in the diet and information from the patient generated subjective global assessment (PG-SGA) tool can provide more specific information [35,36,45,51,62,66,[69][70][71][72][73][78][79][80].…”

Section: Review Of Strategies To Improve Eating Behaviors While Receiving Chemotherapy And/or Radiationmentioning

confidence: 99%

Strategies to Mitigate Chemotherapy and Radiation Toxicities That Affect Eating

et al. 2021

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Background: Cancer and its therapy is commonly associated with a variety of side effects that impact eating behaviors that reduce nutritional intake. This review will outline potential causes of chemotherapy and radiation damage as well as approaches for the amelioration of the side effects of cancer during therapy. Methods: Information for clinicians, patients, and their caregivers about toxicity mitigation including nausea reduction, damage to epithelial structures such as skin and mucosa, organ toxicity, and education is reviewed. Results: How to anticipate, reduce, and prevent some toxicities encountered during chemotherapy and radiation is detailed with the goal to improve eating behaviors. Strategies for health care professionals, caregivers, and patients to consider include (a) the reduction in nausea and vomiting, (b) decreasing damage to the mucosa, (c) avoiding a catabolic state and muscle wasting (sarcopenia), and (d) developing therapeutic alliances with patients, caregivers, and oncologists. Conclusions: Although the reduction of side effects involves anticipatory guidance and proactive team effort (e.g., forward observation, electronic interactions, patient reported outcomes), toxicity reduction can be satisfying for not only the patient, but everyone involved in cancer care.

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Impact of Early Incorporation of Nutrition Interventions as a Component of Cancer Therapy in Adults: A Review

Cited by 28 publications

References 48 publications

Results of the ECHO (Eating habits CHanges in Oncologic patients) Survey: An Italian Cross-Sectional Multicentric Study to Explore Dietary Changes and Dietary Supplement Use, in Breast Cancer Survivors

Results of the ECHO (Eating habits CHanges in Oncologic patients) Survey: An Italian Cross-Sectional Multicentric Study to Explore Dietary Changes and Dietary Supplement Use, in Breast Cancer Survivors

Tumorigenic Potential of Dimethyl Sulfoxide, Anthracene in Fish and Anthracene in Dimethyl Sulfoxide in Rattus Norvegicus

Strategies to Mitigate Chemotherapy and Radiation Toxicities That Affect Eating

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