Impact of dimeric organization of enzyme on its function: the case of photosynthetic water splitting

Jablonský, Jiří; Sušila, Petr; Lazár, Dušan

doi:10.1093/bioinformatics/btn530

Cited by 9 publications

(1 citation statement)

References 21 publications

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“…This observation has been incorporated into various theoretical investigations ( Stirbet et al., 1998 ; Tomek et al., 2001 ; Zhu et al., 2005 ; Lazár, 2009 ). Moreover, the redox states of the Oxygen-Evolving Complex (OEC) ( Delosme and Joliot, 2002 ; Jablonsky and Lazar, 2008 ; Jablonsky et al., 2008 ), in conjunction with the activity of Cytb 6 /f ( Johnson and Berry, 2021 ) and PSI ( Schreiber and Krieger, 1999 ; Schansker et al., 2003 ; Schansker and Strasser, 2005 ; Schansker et al., 2005 ), have been shown to influence the thermal phase (J-I-P rise) of the rapid FI curve.…”

Section: Introductionmentioning

confidence: 99%

Screening rate constants in the simulation of rapid kinetics of chlorophyll a fluorescence using the Morris method

Lyu,

Lin,

Liakopoulos

2024

Front. Plant Sci.

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Chlorophyll a fluorescence, a sensitive and cost-effective probe, is widely used in photosynthetic research. Its rapid phase, occurring within 1 second under intense illumination, displays complex O-J-I-P transients, providing valuable insights into various aspects of photosynthesis. In addition to employing experimental approaches to measure the rapid Fluorescence Induction (FI) kinetics, mathematical modeling serves as a crucial tool for understanding the underlying mechanisms that drive FI dynamics. However, the significant uncertainty and arbitrary nature of selecting model parameters amplify concerns about the effectiveness of modeling tools in aiding photosynthesis research. Therefore, there is a need to gain a deeper understanding of how these models operate and how arbitrary parameter choices may influence their outcomes. In this study, we employed the Morris method, a global Sensitivity Analysis (SA) tool, to assess the significance of rate constants employed in an existing fluorescence model, particularly those linked to the entire electron transport chain, in shaping the rapid FI dynamics. In summary, utilizing the insights gained from the Morris SA allows for targeted refinement of the photosynthesis model, thereby improving our understanding of the complex processes inherent in photosynthetic systems.

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