Impact of different partitioned solvents on chemical composition and bioavailability of Sasa quelpaertensis Nakai leaf extract

Abstract

The leaves of Sasa quelpaertensis Nakai were extracted with 80% ethanol and further partitioned with n-hexane, chloroform, ethyl acetate, n-butanol, and aqueous fractions to evaluate the biological activity through assessment via various in vitro assays, including total phenol content; 1,1-diphenyl-1-picrylhydrazyl (DPPH) and 2,2-azino-bis-(3-ethylbenzothiazothiazoline-6-sulfornic acid (ABTS) radical scavenging; reducing power; α-glucosidase and tyrosinase inhibitory; and alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activity assays. The highest activity was found in the ethyl acetate fraction for all assays and showed stronger DPPH radical scavenging, reducing power, and tyrosinase inhibitory activity than the positive controls (butylated hydroxytoluene, α-tocopherol, and arbutin, respectively). When compared to the ethyl acetate fraction, the n-butanol fraction had lower rates, but it still demonstrated relatively high activity. The activity of the n-hexane fraction was high for DPPH and ABTS radical scavenging activity and contained significant amounts of phenol content, whereas the chloroform fraction possessed the highest reducing power, tyrosinase inhibitory, and ADH and ALDH activity, despite having the lowest phenol content when compared to the other fractions. These findings clearly indicate that S. quelpaertensis Nakai leaves can be a good natural source of antioxidants and tyrosinase inhibitors, as well as ADH and ALDH activity inducers, suggesting that may have potential for treating various diseases and improving human health.

Isolation of flavonoids from Musa acuminata Colla (Simili radjah, ABB) and the in vitro inhibitory effects of its leaf and fruit fractions on free radicals, acetylcholinesterase, 15‐lipoxygenase, and carbohydrate hydrolyzing enzymes

“…Their presence in polar fractions could perhaps explain why polar solvents, such as water and alcohol, are used in indigenous medicine to macerate or prepare most herbal formulations. This finding is in congruent with the result of other studies (Faraone et al, ; Nakamura, Ra, Jee, & Kim, ). Phenolic compounds, which includes flavonoids, are known to exhibit antioxidant activities and are soluble in polar solvents such as alcohol and acetone (Luo, Basile, & Kennelly, ).…”

Assessment of Antioxidant Potential and phytochemical screening of Phenolic Compounds of Gleditsia triacanthos L Pods

“…Extract yield of Gleditsia triacanthos L pods prepared by maceration using increasing polarity solvents showed that the polar extracts (crude methanolic extract, n-butanol and aqueous fractions), were found to contain the highest yields. This result was in full agreements with other studies 7,19,21,22 . The yield is a relative parameter and depends on the plant species studied, the part used in the extraction, the drying and storage conditions, the content of each species in secondary metabolites and the nature of the solvent used in the plant extraction as well as the extraction method itself.…”

Sasa Quelpaertensis Nakai Induced Antidepressant-Like Effect in Ovariectomized Rats

“…Therefore, this study was designed to investigate the effect of oral SQE on the ovariectomized rats with repeated stress and to explore its mechanisms that exhibited the antidepressant-like effect. We intended to administer two different doses of SQE (100 and 300 mg/kg) since SQE chemical composition and bioavailability are well studied in these two doses [28]. Our present data demonstrated that continuous administration of the SQE orally for 2 weeks induced an antidepressant-like effect on the ovariectomized rat with repeated stress.…”

“…Recently, this bamboo grass gained more attention in traditional medicine due to its dietary phytochemicals (including p-coumaric acid and tricin) that boost general health [27][28][29][30][31][32]. It is reported that bamboo leaf extract enhanced the levels of acetylcholine and -aminobutyric acid (GABA) in rat's hippocampus and improved the learning and memory ability of dementia model rats [33].…”