Impact of diabetes on 10-year outcomes of patients with multivessel coronary artery disease in the Medicine, Angioplasty, or Surgery Study II (MASS II) trial

Lima, Eduardo Gomes; Hueb, Whady; Garcia, Rosa Wanda Diez; Pereira, Alexandre C.; Soares, Paulo Rogério; Favarato, Desidério; Garzillo, Cibele Larrosa; Vieira, Ricardo D’Oliveira; Rezende, Paulo Cury; Takiuti, Myrthes Emy; Girardi, Priscyla; Hueb, Alexandre Ciappina; Ramires, José Antônio Franchini; Filho, Roberto Kalil

doi:10.1016/j.ahj.2013.04.017

Cited by 57 publications

(42 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Thus, the generalizability of the results pertains to such a population. Our results corroborate the general observation that diabetic patients have a higher mortality rate than the nondiabetic population under long-term observation in all subsets of coronary disease despite adjusting for baseline differences [1,2,3,4,5,6,7,8,9,10]. Most studies have only addressed survival either in type 1 or type 2 diabetes, separately, or in diabetic patients in general, and we found only 2 recent studies that actually compare survival in both type 1 and 2 diabetics with that of a nondiabetic population [23,24].…”

Section: Discussionsupporting

confidence: 80%

See 1 more Smart Citation

Survival in Type 1 and Type 2 Diabetes in a Population Referred for Invasive Evaluation of Coronary Disease

Mølstad¹,

Rødevand²

2017

Cardiology

View full text Add to dashboard Cite

Objectives: To evaluate long-term and time trends of survival in patients with a clinical diagnosis of type 1 and type 2 diabetes compared to patients without diabetes in a population referred for invasive treatment of coronary disease. Methods: Patients examined for heart disease at the Feiring LHL Clinics from March 1999 until December 2014 were followed for survival until 20 September, 2015. This yielded 43,872 patients with a known survival status including 1,326 (3.0%) patients with type 1 diabetes and 4,564 (10.9%) with type 2 diabetes. Results: Cox regression revealed a hazard ratio (HR) in type 1 and type 2 diabetes, respectively, of 1.78 (95% confidence interval [CI] 1.60-1.99) and 1.29 (95% CI 1.21-1.37). Comparing survival in the treatment periods before and after 2007, patients without diabetes and with type 2 diabetes had a reduced HR of 0.78 (95% CI 0.72-0.84) and 0.76 (95% CI 0.63-0.91), respectively, but there was no reduction in type 1 diabetes (HR 1.03; 95% CI 0.74-1.42). Conclusions: Type 1 and type 2 diabetes have excess long-term mortality. In the nondiabetic and type 2 diabetic patients, a reduction in mortality has been noted in recent years, but has not been observed in type 1 diabetic patients.

show abstract

Section: Discussionsupporting

confidence: 80%

“…It is well established that patients with diabetes mellitus have an increased risk of mortality and morbidity from cardiovascular disease compared to the general population [1,2,3,4,5,6,7,8,9,10]. A number of studies have also been published evaluating the impact of different regimens on the excess mortality observed [11,12,13,14,15].…”

Section: Introductionmentioning

confidence: 99%

Survival in Type 1 and Type 2 Diabetes in a Population Referred for Invasive Evaluation of Coronary Disease

Mølstad¹,

Rødevand²

2017

Cardiology

View full text Add to dashboard Cite

show abstract

“…17) Moreover, complete revascularization was achieved in 41% of PCI and 74% of CABG in the MASS Trial, respectively. 18) A recent post-hoc analysis from the 4-year outcomes of the SYNTAX Trial and Registry showed that angiographic complete revascularization was achieved in only 52.8% of the PCI arm and 66.9% of the CABG arm. 32) Patients with incomplete revascularization had a significantly higher risk of death, MI, and repeat revascularization in both the PCI and CABG groups.…”

Section: Considerations On Randomized Controlled Trialsmentioning

confidence: 99%

“…18) This trial aimed to compare medical therapy, PCI, and CABG in 232 diabetic patients and 379 nondiabetic patients with multivessel CAD. Endpoints evaluated were overall and cardiac mortality.…”

Section: Randomized Controlled Trialsmentioning

confidence: 99%

CABG Versus PCI in the Treatment of Diabetic Patients Affected by Coronary Artery Disease

Nicolini

Agostinelli²,

Vezzani³

et al. 2014

Int. Heart J.

View full text Add to dashboard Cite

SummarySurgical coronary revascularization and percutaneous coronary intervention were demonstrated to be effective treatments for coronary artery disease. However, the optimal revascularization strategy remains unclear in certain patient subsets. The recently published Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease (FREEDOM) trial is a randomized study evaluating the use of CABG versus PCI in diabetic patients with multivessel coronary disease. The purpose of this study was to review the available literature based on randomized trials and observational studies in order to allow clinicians to make evidence-based decisions when treating diabetic patients with multivessel coronary disease. The current evidence suggests that CABG should remain the standard of care for this patient population. (Int Heart J 2014; 55: 469-473)

show abstract

“…Assim, mesmo com a evolução do tratamento da hiperglicemia, pacientes com diabetes e doença arterial coronariana apresentam pior prognóstico cardiovascular, independentemente do tratamento utilizado (8) .…”

Section: Dados Internacionais De Catalogação Na Publicação (Cip)unclassified

Expressão do precondicionamento isquêmico em pacientes com diabetes mellitus tipo 2 e doença arterial coronariana

Rezende¹

Self Cite

View full text Add to dashboard Cite

show abstract

Impact of diabetes on 10-year outcomes of patients with multivessel coronary artery disease in the Medicine, Angioplasty, or Surgery Study II (MASS II) trial

Cited by 57 publications

References 25 publications

Survival in Type 1 and Type 2 Diabetes in a Population Referred for Invasive Evaluation of Coronary Disease

Survival in Type 1 and Type 2 Diabetes in a Population Referred for Invasive Evaluation of Coronary Disease

CABG Versus PCI in the Treatment of Diabetic Patients Affected by Coronary Artery Disease

Expressão do precondicionamento isquêmico em pacientes com diabetes mellitus tipo 2 e doença arterial coronariana

Contact Info

Product

Resources

About