Impact of diabetes mellitus and its control on pulmonary functions and cardiopulmonary exercise tests

El-Habashy, Mahmoud M.; Agha, Mohammed A.; El-Basuni, Hany A.

doi:10.1016/j.ejcdt.2013.09.013

Cited by 13 publications

(26 citation statements)

References 19 publications

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“…Aerobic exercise activities promote energy expenditure, lipid oxidation, insulin sensitivity [30], cardio-respiratory fitness, breathlessness [31], lung function and habitual activity in even in children with cystic fibrosis [32]. As a result of uncontrolled blood glucose levels, there are microvascular complications and reduction in lung ventilatory functions [4,[33][34]. The results of this study also showed significant differences between pre and post treatment pulmonary function parameters mean values.…”

Section: Discussionmentioning

confidence: 72%

Efficiency of Wii aerobic training on pulmonary functions in the Egyptian children with T1DM

Mohammed¹,

Elyazed²

2017

International Journal of Therapies and Rehabilitation Research

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Section: Discussionmentioning

confidence: 72%

Efficiency of Wii aerobic training on pulmonary functions in the Egyptian children with T1DM

Mohammed¹,

Elyazed²

2017

International Journal of Therapies and Rehabilitation Research

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“…Other study by Zeneldin et al [19] published in 2015 and Irfan et al also had higher mean age among the control subjects [17]. Anandhalakshmi S et al [20] and El-Habashy MM et al (2013) [21] scrutinized that in both diabetic and non-diabetic group mean age of the patients was younger (44.8± 8.9 vs. 39.4 ± 11.7), due to small sample size these studies showed dissimilar results. [22,23].…”

Section: Discussionmentioning

confidence: 96%

Diabetic: A Comparative Study

Dhungel

Wassem

Dhungel³

2017

Janaki Med. Coll. J. Med. Sci.

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Background and Objectives: Type II diabetes mellitus (DM) is particularly common medical disorder and is leading cause of morbidity worldwide. The complication of DM is due to micro or macro vascular damage. The presence of an extensive microvascular circulation and abundant connective tissue in the lungs raises the possibility that lung tissue may be a target organ in diabetic patients and thus pulmonary function test can be affected by DM. This study was designed to compare pulmonary function test between Type II diabetic and non-diabetic individuals; and, with the duration of DM. Material and Methods:This cross sectional comparative study was conducted at King Edward Medical University, Lahore Pakistan. Total sample consist of 91 diabetic and 91 non-diabetic grouped as group A and group B. FEV1, FVC, FEV1/FVC ratio, and PEFR were compared within two groups and with the duration of DM.Results: Total 182 sample with mean age 53.15.90 years, with 91(50%) male and 91(50%) female. Group A and B had 91(50%) sample each. Mean value of FVC, FEV1 and PEFR showed statistically significant difference among the both group. Mean of FVC decreases significantly with the increasing duration of DM; although, is not significant with FEV1, FEV1/FVC ratio, and PEFR. Conclusion:Diabetic group showed significantly impaired pulmonary functions test as FEV1, FVC, and PEFR as compare to non-diabetic group.

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“…In addition, T1DM seems accelerating the respiratory ageing. Tables 1E and 2E describe, respectively, the five international and the four African published studies [10,14,17,[19][20][21][22][23][24]. The above studies have controversial conclusions and used limited methodology:…”

Section: Discussionmentioning

confidence: 99%

“…That was hence the first results in the literature suggesting that the lung may be a ''target organ'' of T1DM. Since then, studies analysing T1DM ventilatory mechanics and/or pulmonary exchanger are more numerous with controversial conclusions: no effect [9][10][11][12][13], abnormal data [14][15][16][17][18][19][20][21][22][23][24][25][26][27] with conflicting reports on the nature of spirometric alterations: restrictive [14][15][16][17] and/or large-airways obstructive [16,17]-ventilatory-defects (respectively, RVD, and LAOVD) and/or decreased DLCO [14,15,18,23,26], and normal spirometry data but decreased DLCO [27]. In addition, the majority of these studies [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23]…”

Section: Introductionmentioning

confidence: 99%

“…In addition, the majority of these studies [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] used limited methodology: combination of the two types of DM [14,[19][20][21][22]; inclusion of T1DM patients with a high difference in disease duration [17]; inclusion of both controlled and uncontrolled T1DM [21]; lack of control groups such as healthy-subjects [17,19]; measurements of expiratory flows only [14,17,20,21,24], without measurement of lung volumes and/or lung-hyperinflation; non-application [10,17,21,22,24] of the latest lung function international recommendations [28][29][30], no report of the applied lung function guidelines [14,19,20,23]; use of unspecified spirometric norms [10,…”

Section: Introductionmentioning

confidence: 99%

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Lung function in poorly controlled type 1 North African diabetic patients: A case-control study

Slim

Khalaf

Latiri

et al. 2015

Egyptian Journal of Chest Diseases and Tuberculosis

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Aim: To compare the lung function parameters of poorly controlled type-1-diabetesmellitus (T1DM) patients with age-; height and sex-matched healthy-non-smokers (HNS).Population and methods: Subjects aged 35-60 Yrs who have a poorly controlled T1DM (glycated-Haemoglobin level >7%) with a disease history of more than 10 Yrs (n = 14) and HNS subjects (n = 14) were recruited. Clinical, anthropometric and fasting biological data were This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Aging; Case-control study collected. Plethysmographic data (flows, volumes, estimated-lung-age (ELA), lung-capacity-totransfer-carbon-monoxide (DLCO)) were measured. Large-airway-obstructive-ventilatory-defect (LAOVD) was defined as first-second-forced-expiratory-volume (FEV 1 )/forced-vital-capacity (FVC) below the lower-limit-of-normal (LLN). Restrictive-ventilatory-defect (RVD) was defined as total-lung-capacity (TLC) < LLN. Lung-hyperinflation was defined as residual-volume (RV) > upper-limit-of-normal. Student t-test and chi-2 test were used to compare plethysmographic data and profiles of the two groups.Results: The two groups were matched in chronological-lung-age (CLA) (respectively 47 ± 7 vs. 50 ± 8 Yrs) and sex (7 males and 7 females in each group) and height. Compared to the HNS group, the T1DM one had significantly lower FEV 1 , FVC, slow-vital-capacity and maximal-midexpiratory-flow (respectively 99 ± 11% vs. 83 ± 11%, 99 ± 9% vs. 86 ± 11%, 80 ± 8% vs. 67 ± 15% and 98 ± 23% vs. 72 ± 23%), had significantly higher TLC and RV (respectively, 105 ± 20% vs. 123 ± 24% and 108 ± 22% vs. 131 ± 24%) and had significantly higher percentage of subjects with lung-hyperinflation (7.1% vs. 43.0%). Both groups had similar percentages of LAOVD and RVD and similar corrected DLCO values. ELA of the T1DM group (57 ± 10 Yrs) was significantly higher than CLA.Conclusion: Poorly controlled T1DM seems to alter ventilatory mechanics without effect on the alveolo-capillary-membrane. In addition, it accelerates the respiratory ageing.

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Impact of diabetes mellitus and its control on pulmonary functions and cardiopulmonary exercise tests

Cited by 13 publications

References 19 publications

Efficiency of Wii aerobic training on pulmonary functions in the Egyptian children with T1DM

Efficiency of Wii aerobic training on pulmonary functions in the Egyptian children with T1DM

Diabetic: A Comparative Study

Lung function in poorly controlled type 1 North African diabetic patients: A case-control study

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