“…Replacement donations thus remained the only feasible solution to severe blood shortages being faced by the country and the need to meet the increased demand for blood due to haemolytic episodes, road traffic accidents, surgical interventions, maternal comorbidities, severe anaemia, haemorrhagic shocks, cancer related issues and other medical conditions. Study showed the need to address the protracted issue of COVID-19 pandemic holistically with considerations to its negative impacts on blood and blood products availability and supply [27,29]. Another study by Okoroiwu et al (2018) on voluntary donations during COVID-19 pandemic in Nigeria showed similar trend of negative impacts [31].…”
Background: Transfusion transmissible hepatitis (TTH) is a global health problem and the incriminating agents such as hepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis E virus (HEV) continue to pose serious threats to blood safety. The aim of this study was to determine the seroprevalence of HBV, HCV and HEV and relate the outcomes with blood donation type, age and gender and confirm any significant associations.
Materials and Methods: In this cross-sectional study, Hepatitis B surface antigen (HBsAg) and antibody to HCV were determined with Diaspot and Lab Acon immunochromatographic ELISA-based test devices. Antibodies to HEV were first determined with Biopanda lateral flow device followed by ELISA assay for sero-reactive HEV immunoglobulins M and immunoglobulin G (IgM and IgG) antibodies.
Results: A total of 370 prospective blood donors between 18 and 55 years old (mean 31.2 ± 7.6 years) who presented for blood donation at FETHI Blood Bank were screened. Overall male: female ratio was 7:1. Cummulative hepatitis seroprevalence of 8.1% was found mainly among the replacement blood donors (RBD) and consist of 4.3%, 1.6%, 1.1%, 0.8% and 0.3% serologic evidence of HBsAg, anti-HCV, HEV IgM, both HEV IgM & HEV IgG, and HEV IgG antibodies. Blood donors aged 18 – 45 years were most affected with evident significant association between the age group of donors and TTH seroprevalence. Cummulative hepatitis seroprevalence was 0% among voluntary blood donors, and 9.1% and 0.3% among the male and female RBD respectively. There was significant association between the pathogens and RBD, though the association with male gender was clinically but not statistically significant.
Conclusion: The high transfusion transmissible hepatitis seroprevalence among RBD called for promoting voluntary donations. Comparable prevalence of HEV antibodies with that of HCV called for its inclusion in the TTIs screening algorithm to ascertain optimal blood safety in Nigeria.
“…Replacement donations thus remained the only feasible solution to severe blood shortages being faced by the country and the need to meet the increased demand for blood due to haemolytic episodes, road traffic accidents, surgical interventions, maternal comorbidities, severe anaemia, haemorrhagic shocks, cancer related issues and other medical conditions. Study showed the need to address the protracted issue of COVID-19 pandemic holistically with considerations to its negative impacts on blood and blood products availability and supply [27,29]. Another study by Okoroiwu et al (2018) on voluntary donations during COVID-19 pandemic in Nigeria showed similar trend of negative impacts [31].…”
Background: Transfusion transmissible hepatitis (TTH) is a global health problem and the incriminating agents such as hepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis E virus (HEV) continue to pose serious threats to blood safety. The aim of this study was to determine the seroprevalence of HBV, HCV and HEV and relate the outcomes with blood donation type, age and gender and confirm any significant associations.
Materials and Methods: In this cross-sectional study, Hepatitis B surface antigen (HBsAg) and antibody to HCV were determined with Diaspot and Lab Acon immunochromatographic ELISA-based test devices. Antibodies to HEV were first determined with Biopanda lateral flow device followed by ELISA assay for sero-reactive HEV immunoglobulins M and immunoglobulin G (IgM and IgG) antibodies.
Results: A total of 370 prospective blood donors between 18 and 55 years old (mean 31.2 ± 7.6 years) who presented for blood donation at FETHI Blood Bank were screened. Overall male: female ratio was 7:1. Cummulative hepatitis seroprevalence of 8.1% was found mainly among the replacement blood donors (RBD) and consist of 4.3%, 1.6%, 1.1%, 0.8% and 0.3% serologic evidence of HBsAg, anti-HCV, HEV IgM, both HEV IgM & HEV IgG, and HEV IgG antibodies. Blood donors aged 18 – 45 years were most affected with evident significant association between the age group of donors and TTH seroprevalence. Cummulative hepatitis seroprevalence was 0% among voluntary blood donors, and 9.1% and 0.3% among the male and female RBD respectively. There was significant association between the pathogens and RBD, though the association with male gender was clinically but not statistically significant.
Conclusion: The high transfusion transmissible hepatitis seroprevalence among RBD called for promoting voluntary donations. Comparable prevalence of HEV antibodies with that of HCV called for its inclusion in the TTIs screening algorithm to ascertain optimal blood safety in Nigeria.
“…Blood supply in Botswana has been in chronic shortage for years and suffered an acute crisis in 2020 [10]. In 2021, Author co-conducted workshops with Gaborone city residents, entrepreneurs from a local incubator, and National Blood Transfusion Services (NBTS) staff to understand the reasons behind the chronic blood shortage [9].…”
What role can the commons play in improving citizen trust in healthcare services? We explore this question in the context of the chronic blood supply shortage in Botswana, where the Indigenous kgotla village governance system operates alongside the republican state. To address barriers to trust in the blood services ecosystem, we review the public-commons partnership model as a commons ecosystem model that could support participatory design of blood services between the kgotla and state. We apply this model to the ecosystem mapping tool used in the Jigsaw framework, a method previously used in Botswana to support ecosystem visualization, to prompt state consideration of this alternative public-commons partnership as a solution to the blood supply shortage. We also explore the re-visualized ecosystem as a pluriversal commons, where the kgotla and state cosmologies must interact to solve the collective action challenge of blood supply.
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