Impact of coronavirus infection on cognitive functions in elderly patients

Potupchik, T.; Эверт, Л. С.; Kostyuchenko, Yu.

doi:10.29296/25877305-2021-06-08

Cited by 3 publications

(1 citation statement)

References 6 publications

(6 reference statements)

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“…The impact of these diseases, except for type I DM, is also most pronounced in patients aged 60 years and older [13]. Older patients are more vulnerable to neuropsychiatric and cognitive impairment in COVID-19, and pre-existing disorders of this spectrum including dementia tend to progress after coronavirus infection [14].…”

Section: Covid-19 In Adultsmentioning

confidence: 99%

Factors affecting the severity of COVID-19 and the development of complications

Radygina,

Mochalova

2023

Microbiology Independent Research Journal (MIR Journal)

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Due to the prevalence and diversity of both symptoms and outcomes of COVID-19, understanding the factors that determine the risk of the severe course of this disease and its possible complications is of particular importance. In this review, we present the information on the specifics of COVID-19 pathogenesis and give a theoretical justification for the factors that determine the course of this disease in patients of different age groups, patients with chronic pathology, and pregnant women. Particular attention is paid to the post-COVID syndrome.

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Section: Covid-19 In Adultsmentioning

confidence: 99%

Factors affecting the severity of COVID-19 and the development of complications

Radygina,

Mochalova

2023

Microbiology Independent Research Journal (MIR Journal)

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Факторы, Влияющие На Тяжесть Течения COVID-19 И Развитие Осложнений

Радыгина,

Мочалова

2023

Microbiology Independent Research Journal (MIR Journal)

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В связи с широким распространением и «многоликостью» как симптоматики, так и исходов COVID-19 особую актуальность приобретает понимание факторов, определяющих риск тяжелого течения заболевания и возможных осложнений. В обзоре представлена информация об особенностях патогенеза COVID-19, дали теоретическое обоснование факторов, обусловливающих особенности заболевания у пациентов разных возрастных групп, беременных, а также при хронических патологиях. Отдельное внимание уделено постковидному синдрому.

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Clinical and laboratory rationale for use of correctors of metabolism for treatment of patients with new coronavirus infection COVID-19 in acute period with background of cerebrovascular disease

Соколова

Privalova

Zueva³

et al. 2022

Medicinskij alfavit

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Objective. The aim of the study was to evaluate the effectiveness of the drug Mildronate in the complex therapy of patients with a new coronavirus infection COVID-19 in the acute period and the background of cerebrovascular disease.Material and methods. The material for the study was the medical records of 210 patients (140 women and 70 men) who had COVID-19 coronavirus infection against the background of cerebrovascular pathology in the period from 04.10.2020 to 12.31.2021. 120 patients (75 women and 45 men) received the drug Mildronate as part of complex therapy, 90 patients (55 women 35 men) made up the control group, received complex treatment without the use of the drug Mildronate. Patients in both groups were comparable in age, the average age was 76.5 years (from 50 to 93 years). Groups according to nosological forms were distributed as follows: in the main group – ischemic stroke of various localization – 70 patients (48 women and 22 men), chronic cerebrovascular insufﬁciency of varying severity – 50 patients (27 women and 23 men); in the control group – ischemic stroke of various localization was in 50 patients (36 women and 14 men), chronic cerebrovascular insufﬁciency – 40 patients (19 women and 21 men). To correct chronic hypoxia, the drug Mildronate was chosen, which is a blocker of fatty acid oxidation, has a multicomponent effect, stabilizes microcirculation under conditions of ischemia and hypoxia. Also, Mildronate is one of the universal cytoprotectors with a pronounced neuro-, cardio- and angioprotective effect, which goes well with drugs of other pharmacological groups.Results. The drug Mildronate is a blocker of fatty acid oxidation, has a multicomponent effect, stabilizes microcirculation in conditions of ischemia and hypoxia. According to the observations, it can be noted that the neurological status during mildronate therapy has a more signiﬁcant regression trend with good rehabilitation potential – 56.0% of patients can serve themselves independently, while patients in the control group reached a level of 9 points only in 51.0% of cases. A signiﬁcant neurological defect remained in the main group in 6.2% of patients, in the control group this ﬁgure was 8.8%.

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Impact of coronavirus infection on cognitive functions in elderly patients

Cited by 3 publications

References 6 publications

Factors affecting the severity of COVID-19 and the development of complications

Factors affecting the severity of COVID-19 and the development of complications

Факторы, Влияющие На Тяжесть Течения COVID-19 И Развитие Осложнений

Clinical and laboratory rationale for use of correctors of metabolism for treatment of patients with new coronavirus infection COVID-19 in acute period with background of cerebrovascular disease

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