Impact of Childhood Stress on Psychopathology

Abstract

MRI studies have shown that exposure to trauma at an early age can result in several neurostructural changes, such as the reduction of the hippocampus and corpus callosum. Cognitive performance and functioning are also altered in this population. Finally, childhood stress is related to an increased risk of developing MD such as depression, bipolar disorder, schizophrenia and substance abuse. We conclude that there is robust evidence of the role of the environment, specifically adverse childhood experiences, in various aspects of MD.

Clinical characteristics and influence of childhood trauma on the prodrome of bipolar disorder

“…Patients with BD exhibit higher vulnerability to traumatic events during childhood. 21 In addition, BD seems to be a stresssensitive disorder, with the first mood episode often being triggered by psychosocial stressors. 21,22 Childhood trauma also appears to impact the course of the illness, being associated with earlier illness onset, an increased number of comorbidities, and suicidal behavior.…”

“…21 In addition, BD seems to be a stresssensitive disorder, with the first mood episode often being triggered by psychosocial stressors. 21,22 Childhood trauma also appears to impact the course of the illness, being associated with earlier illness onset, an increased number of comorbidities, and suicidal behavior. 20,23 Although childhood trauma is assumed to have an important role in the early expression of symptoms in BD, to the best of our knowledge, no studies that investigated the prodromal period of this disorder have systematically evaluated the presence of childhood trauma or its influence on the prodromal manifestations of BD.…”

Propiedades psicométricas de la escala de estrés cotidiano infantil en niños de 3ero a 5to grado de primaria de colegios de Lima Metropolitana

“…Asimismo, se ha estudiado que el estrés experimentado durante la vida temprana puede generar alteraciones en la estructura cerebral, perturbando funciones importantes y generando un impacto a largo plazo (Brietzke et al, 2012). De esta manera, las personas que han experimentado estrés de niños tienen una alta probabilidad de experimentar síntomas de ansiedad o de depresión en la adolescencia o adultez (Tsoory,…”

“…Esto podría contribuir a generar estrategias de prevención para evitar desventajas y malestar en áreas académicas, sociales y familiares . De esta manera, se reduciría el impacto que el estrés tiene a nivel neurológico (Brietzke et al, 2012) así como la frecuente incidencia en la adultez (Escobar et al, 2013).…”

“…Algunos eventos de la vida temprana, como complicaciones de embarazo, traumas infantiles o abuso de sustancias, interactúan con rasgos genéticos y pueden conducir a trastornos del neurodesarrollo y trastornos mentales en la adultez temprana (Brietzke et al, 2012). Así, se ha comprobado que el estrés infantil tiene consecuencias negativas en el desarrollo de niños y adolescentes y que estas persisten hasta la adultez (Escobar et al, 2013).…”