Impact of cardiovascular autonomic neuropathy in gastroesophageal reflux diseases (GERD)– A clinical study

G, Thilip Kumar; R, Jamuna Rani; Kumar, Kanwal; Lalithambigai, G; Maruthy, K N; Qairunnisa, A

doi:10.22376/ijpbs.2019.10.2.b15-22

Cited by 10 publications

(13 citation statements)

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“…Coumarins are chemically familiar as 1,2-benzopyranone and quite available in plants were identied rstly as an oxygen heterocycle in 1820's. 16 Their distinguished biological, therapeutic and pharmacological efficiencies e.g. antimicrobial and anti-inammatory, 17,18 antioxidant and antibacterial activities, 19 made them materials of interest in medicinal and organic chemists.…”

Section: Introductionmentioning

confidence: 99%

Sulfamic acid incorporated HKUST-1: a highly active catalyst and efficient adsorbent

et al. 2020

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Section: Introductionmentioning

confidence: 99%

Sulfamic acid incorporated HKUST-1: a highly active catalyst and efficient adsorbent

et al. 2020

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“…Antioxidants may act as free radical scavengers, reducing agents, quenching agents and/or activators of cellular antioxidant enzymes to prevent free radical damage in biological systems . Also, most of the bacteria and fungi showed resistance to classical antibiotics, and the discovery of new active compounds is a matter of urgency …”

Section: Introductionmentioning

confidence: 99%

Application of the Fe₃O₄@1,10‐phenanthroline‐5,6‐diol@Mn nano‐catalyst for the green synthesis of tetrazoles and its biological performance

Habibi

Heydari

Gil

et al. 2017

Applied Organom Chemis

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The Fe3O4 magnetic particles were modified with 1,10‐phenanthroline‐5,6‐diol (Phen) and the related Mn complex (Fe3O4@Phen@Mn) synthesized as a heterogeneous catalyst to be used for the one‐pot three‐component synthesis of various tetrazoles. The catalysts were characterized by several methods, such as the elemental analysis, FT‐IR, X‐ray powder diffraction, dispersive X‐ray spectroscopy, scanning electron microscopy, transmission electron microscopy, dynamic light scattering, thermogravimetric‐differential thermal analysis, vibrating sample magnetometer and X‐ray photoelectron spectroscopy. In addition, the antioxidant and antibacterial activities of the catalyst and its Phen ligand were in vitro screened with 2,2‐diphenyl‐1‐picrylhydrazyl by free radical scavenging methods. Results showed that the synthesized compounds possess strong antioxidant activity (IC50; 0.172 ± 0.005 mg ml−1) as well as a good antibacterial potential in comparison to standards.

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“…Coumarin and its derivatives represent one of the most active classes of compounds possessing a wide spectrum of biological activity. The synthesis, and pharmacological and other properties of coumarin derivatives have been studied and reviewed (Kumar et al, 2015;Kubrak et al, 2017;Srikrishna et al, 2018;Venugopala et al, 2013). Many of these compounds have proven to be active as antibacterial, antifungal, anti-inflammatory, anticoagulant, anti-HIV and antitumor agents.…”

Section: Chemical Contextmentioning

confidence: 99%

The crystal structures of two new coumarin derivatives: 2-(4-{2-[(2-oxo-2H-chromen-4-yl)oxy]acetyl}piperazin-1-yl)acetamide and N-(2,4-dimethoxybenzyl)-2-[(2-oxo-2H-chromen-4-yl)oxy]acetamide

Abuthahir¹,

NizamMohideen²,

Viswanathan

et al. 2019

Acta Cryst E

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The title compounds, 2-(4-{2-[(2-oxo-2H-chromen-4-yl)oxy]acetyl}piperazin-1-yl)acetamide, C17H19N3O5, (I), and N-(2,4-dimethoxybenzyl)-2-[(2-oxo-2H-chromen-4-yl)oxy]acetamide, C20H19NO6, (II), are new coumarin derivatives. In compound (I), the six-membered piperazine adopts a chair conformation. The dihedral angles between the mean planes of the chromene ring and amide plane is 82.65 (7)° in (I) and 26.2 (4)° in (II). The dihedral angles between the mean planes of the chromene ring and the four planar C atoms of the piperazine ring in (I) and the benzene ring in (II) are 87.66 (6) and 65.0 (4)°, respectively. There are short intramolecular contacts in both molecules forming S(5) ring motifs, viz. N—H...N and C—H...O in (I), and N—H...O and C—H...N in (II). In the crystals of both compounds, molecules are linked by N—H...O hydrogen bonds, forming chains along [1\overline{1}0] in (I) and [010] in (II). The chains are linked by C—H...O hydrogen bonds, forming layers parallel to the ab plane in the crystals of both compounds. In the crystal of (I), there are also C—H...π and offset π–π interactions [intercentroid distance = 3.691 (1) Å] present within the layers. In the crystal of (II), there are only weak offset π–π interactions [intercentroid distance = 3.981 (6) Å] present within the layers. The intermolecular contacts in the crystals of both compounds have been analysed using Hirshfeld surface analysis and two-dimensional fingerprint plots.

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Impact of cardiovascular autonomic neuropathy in gastroesophageal reflux diseases (GERD)– A clinical study

Cited by 10 publications

References 0 publications

Sulfamic acid incorporated HKUST-1: a highly active catalyst and efficient adsorbent

Sulfamic acid incorporated HKUST-1: a highly active catalyst and efficient adsorbent

Application of the Fe₃O₄@1,10‐phenanthroline‐5,6‐diol@Mn nano‐catalyst for the green synthesis of tetrazoles and its biological performance

The crystal structures of two new coumarin derivatives: 2-(4-{2-[(2-oxo-2H-chromen-4-yl)oxy]acetyl}piperazin-1-yl)acetamide and N-(2,4-dimethoxybenzyl)-2-[(2-oxo-2H-chromen-4-yl)oxy]acetamide

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Impact of cardiovascular autonomic neuropathy in gastroesophageal reflux diseases (GERD)– A clinical study

Cited by 10 publications

References 0 publications

Sulfamic acid incorporated HKUST-1: a highly active catalyst and efficient adsorbent

Sulfamic acid incorporated HKUST-1: a highly active catalyst and efficient adsorbent

Application of the Fe3O4@1,10‐phenanthroline‐5,6‐diol@Mn nano‐catalyst for the green synthesis of tetrazoles and its biological performance

The crystal structures of two new coumarin derivatives: 2-(4-{2-[(2-oxo-2H-chromen-4-yl)oxy]acetyl}piperazin-1-yl)acetamide and N-(2,4-dimethoxybenzyl)-2-[(2-oxo-2H-chromen-4-yl)oxy]acetamide

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Application of the Fe₃O₄@1,10‐phenanthroline‐5,6‐diol@Mn nano‐catalyst for the green synthesis of tetrazoles and its biological performance