Impact of Bariatric Surgery on the Saliva of Patients with Morbid Obesity

Hashizume, Lina Naomi; Bastos, Lucelen Fontoura; Cardozo, Débora Deus; Hilgert, Juliana Balbinot; Hugo, Fernando Neves; Stein, Airton Tetelbom; Souto, Kátia Elisabete Pires; Meinhardt, Nelson Guardiola

doi:10.1007/s11695-015-1741-4

Cited by 23 publications

(28 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The impairment in salivary buffer capacity may lead to a reduced protection of the teeth, which are more susceptible to the development of dental caries and halitosis (1). Although the salivary pH found in this sample of individuals within the normal range of 6.8-7.5 (55,56), the mean pH found in the analysis of buffer capacity may be considered low (57). Considering these findings, a multidisciplinary guidance is a paramount for individuals with morbid obesity to improve their oral and general health conditions.…”

Section: Discussionmentioning

confidence: 93%

Oral Health and Nutritional Characteristics of Adults With Morbid Obesity: A Multivariate Analysis

et al. 2020

View full text Add to dashboard Cite

The relationship between oral health and nutritional aspects are complex, especially in individuals with chronic diseases and comorbidities, such as morbid obesity. Thus, the aim of the present study was to identify oral health and nutritional-related patterns in 113 individuals, aged 19–68 years (92 females), seeking treatment for morbid obesity. Sociodemographic variables and medical records were examined, in addition to the consumption of fruit, vegetables, candies, and processed foods. Measures of body mass index, neck, waist and hip, caries experience (DMFT index), Community Periodontal Index (CPI index), and salivary physicochemical aspects were gathered. Aspects of oral health-related quality of life and symptoms of dry mouth were evaluated by means of Oral Health Impact Profile (OHIP-14) and Xerostomia Inventory-XI questionnaires. K-means cluster analysis and, subsequently, comparisons between clusters (one-way ANOVA) were performed (α = 5%). Three clusters were generated: Cluster 1 (labeled “Young”; n = 77) was characterized by younger participants with higher BMI, who reported the use of distractors while eating, the smallest number of meals/day, and who consumed sweetened drinks and processed food the day before. Cluster 2 (labeled “Diabetic individuals”; n = 12) was characterized by older participants with the highest proportion of diabetic participants (100% were diabetic; 73% insulin users), lower BMI, higher DMFT index and OHIP-14 and xerostomia scores, and who reported having consumed fruit and vegetables the day before. Finally, Cluster 3 (labeled “Poor periodontal health”; n = 24) was characterized by participants with the worse periodontal condition (higher CPI), and lower salivary flow, pH, and buffer capacity. Cluster 1 and 2 were the groups that showed higher demand for nutritional and dietetic counseling, because of the poor eating behavior and higher serum glucose levels, respectively. On the other hand, Cluster 2 and 3 showed the higher demand for oral rehabilitation and dental treatment because of the loss of teeth and worse periodontal condition, respectively, besides the need for dietetic counseling. This sample of individuals with morbid obesity showed very unique oral-health and nutritional characteristics and special needs patterns that should be identified to adjust or change unhealthy habits, thus improving the assistance of this condition.

show abstract

Section: Discussionmentioning

confidence: 93%

Oral Health and Nutritional Characteristics of Adults With Morbid Obesity: A Multivariate Analysis

et al. 2020

View full text Add to dashboard Cite

show abstract

“…In contrast to the gut microbiome, the salivary microbiome is likely not directly affected by the bariatric surgery, but its composition can be altered indirectly—salivary glucose decreases with body weight loss in diabetic patients with obesity which could enhance growth of bacterial species that prefer a less acidic oral environment 8 , 30 . The post-surgery period is characterized by an increased frequency of meals throughout 31 , which can result in an increase of pathogenic bacteria in the oral cavity, if effective oral hygiene is not practiced 32 . Another factor which might influence salivary microbiome composition is the gastroesophageal reflux.…”

Section: Discussionmentioning

confidence: 99%

Salivary microbiome composition changes after bariatric surgery

Džunková

Lipták

Vlková

et al. 2020

Sci Rep

View full text Add to dashboard Cite

Recent studies show that the salivary microbiome in subjects with obesity differ from those without obesity, but the mechanism of interaction between the salivary microbiome composition and body weight is unclear. Herein we investigate this relation by analyzing saliva samples from 35 adult patients with obesity undergoing bariatric surgery. Our aim was to describe salivary microbiome changes during body weight loss on an individual-specific level, and to elucidate the effect of bariatric surgery on the salivary microbiome which has not been studied before. Analysis of samples collected before and 1 day after surgery, as well as 3 and 12 months after surgery, showed that the salivary microbiome changed in all study participants, but these changes were heterogeneous. In the majority of participants proportions of Gemella species, Granulicatella elegans, Porphyromonas pasteri, Prevotella nanceiensis and Streptococcus oralis decreased, while Veillonella species, Megasphaera micronuciformis and Prevotella saliva increased. Nevertheless, we found participants deviating from this general trend which suggests that a variety of individual-specific factors influence the salivary microbiome composition more effectively than the body weight dynamics alone. The observed microbiome alternations could be related to dietary changes. Therefore, further studies should focus on association with altered taste preferences and potential oral health consequences.

show abstract

“…They detected high C. albicans levels both before and after the intervention and elevated S. mutans levels 6 months after bariatric surgery. However, they also reported that the patients with obesity in their study suffered from a number of chronic systemic comorbidities such as diabetes, for which they were treated with various medications and were prosthesis users, all of which predispose to the expansion of C. albicans [12]. None of these predisposing factors was present in our study, yet in addition to C. albicans, non-albicans Candida species such as C. dubliniensis, C. kefyr, and C. lusitaniae emerged after surgery.…”

Section: Discussionmentioning

confidence: 99%

Follow-up Study of Microflora Changes in Crevicular Gingival Fluid in Obese Subjects After Bariatric Surgery

et al. 2020

View full text Add to dashboard Cite

The objective of our study was to investigate the effect of weight loss on the crevicular microflora following bariatric surgery. Crevicular fluid samples were taken from 57 subjects: 22 were in the normal control group; 18 in the obese control group; and 17 patients had had bariatric surgery, who underwent a repeat sampling 6 to 12 months after the operation. Crevicular fluid samples were analyzed by MALDI-TOF MS analysis. After surgery and weight loss, the mean germ count increased, albeit not significantly. Also, Candida albicans and non-albicans Candida species: C. dubliniensis, C. kefyr, and C. lusitaniae appeared after surgery (p < 0.05) in subjects where Neisseria was either absent throughout or eliminated after surgery. However, periodontitis did not develop during this time in our subjects.

show abstract

Impact of Bariatric Surgery on the Saliva of Patients with Morbid Obesity

Abstract: The results suggest that the salivary levels of mutans streptococci increase following bariatric surgery in morbidly obese patients.

Cited by 23 publications

References 19 publications

Oral Health and Nutritional Characteristics of Adults With Morbid Obesity: A Multivariate Analysis

Oral Health and Nutritional Characteristics of Adults With Morbid Obesity: A Multivariate Analysis

Salivary microbiome composition changes after bariatric surgery

Follow-up Study of Microflora Changes in Crevicular Gingival Fluid in Obese Subjects After Bariatric Surgery

Contact Info

Product

Resources

About