Impact of Bariatric Surgery on Comorbidities

Kaul, Ashutosh; Sharma, Jyoti

doi:10.1016/j.suc.2011.08.003

Cited by 52 publications

(27 citation statements)

References 145 publications

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“…Combination of calcium blocker e.g amlodipine or vasodilating ββ or lower strength diuretic with potent RAAS blockade can negate this risk [6,21,29,31,[62][63][64][65][66][67][68][69]. Finally, cashing in on post-op weight loss with extended rehab and support are factors to discuss at unit case conferences, and when all options fail bariatric surgery in selected patients [15,70,71].…”

Section: Beta Blockersmentioning

confidence: 99%

Do We Need A Wider Therapeutic Paradigm For Heart Failure With Comorbidities?: A Remote Australian Perspective

Iyngkaran¹,

Thomas²

2016

Health Care: Current Reviews

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Forty percent of CHF clients can suffer with up to five or more comorbidity, a rate that is likely higher in the NT. Large CHF trials AbstractCongestive Heart Failure a leading cause of morbidity and mortality is often associated with comorbidities and with it polypharmacy. Improved pathophysiological understanding, the available therapeutics, clinical guidelines and structured programs for comprehensive care have not benefited all clients in the Northern Territory of Australia. The Northern Territory has both a unique geography and demography including a sizeable Indigenous population. Additional factors that can affect heart failure management are prevalent in remote areas and are not well addressed within randomized controlled trials. This review is focused on building a case for widening the therapeutic paradigm for heart failure with comorbidities. We focus on a brief overview of heart failure and its associated comorbidities, the common overlapping physiological processes, the interpretation of the external validity of trial evidence, and finally exploring the available evidence for the important therapies within the guidelines. A need to consider a wider therapeutic paradigm may also have relevance for clients in other health systems.

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Section: Beta Blockersmentioning

confidence: 99%

Do We Need A Wider Therapeutic Paradigm For Heart Failure With Comorbidities?: A Remote Australian Perspective

Iyngkaran¹,

Thomas²

2016

Health Care: Current Reviews

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“…[5][6][7][8][9][10] Está também descrita uma melhoria geral da qualidade de vida dos pacientes submetidos a este procedimento. 11,12 Contudo, os resultados obtidos após este tipo de intervenção não são uniformes, existindo casos em que a perda de peso é insatisfatória, pelo que se tem tentado estudar quais os fatores relacionados com uma menor perda de peso em alguns doentes.…”

Section: 56unclassified

“…13,14,21,22 Em termos de evolução após cirurgia bariátrica, os estudos não são unânimes relativamente a este tópico, sendo que em alguns deles não são referidas melhorias significativas em termos de saúde mental. 10 Noutros casos, verificaram-se melhorias em termos de patologia depressiva ou ansiosa, com melhores resultados para a depressão. 12,18,19,23 A diabetes mellitus tipo 2 e as perturbações do foro psicológico/psiquiátrico são problemas que ocorrem em simultâneo e que se poderão relacionar entre si, sendo importante compreender a sua evolução após realização de cirurgia bariátrica e a sua influência nos resultados da cirurgia.…”

Section: 17unclassified

Diabetes Mellitus Tipo 2, Depressão e Alterações do Comportamento Alimentar em Doentes Submetidos a Cirurgia Bariátrica

Brandão¹,

Pinho

Arrojado³

et al. 2016

Acta Med Port

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Resultados: Verificou-se melhoria relativamente à variável dicotómica diabetes mellitus tipo 2 após a cirurgia (χ 2 (1) = 26,132, p < 0,001). Não ocorreu melhoria significativa em termos de patologia psiquiátrica quando a análise foi controlada para o tipo de cirurgia. Encontrámos uma associação significativa entre as variáveis em estudo no pós-cirúrgico e a perda de peso. Este modelo explica 27% da variação do peso após a cirurgia (R 2 = 0,265) e é significativo F (3,33) = 2,981, p = 0,038. Discussão: A diabetes mellitus tipo 2, patologia depressiva ou do comportamento alimentar mostraram estar relacionados com a perda de peso. Não ficou esclarecido em que sentido esta relação é estabelecida, nem a relação que estas variáveis metabólicas e psicológicas possam ter entre si ao longo do período pós cirurgia bariátrica. Conclusão: A diabetes mellitus tipo 2 evoluiu favoravelmente após a cirurgia. Diabetes mellitus tipo 2, depressão e patologia alimentar no período pós-cirúrgico associaram-se a menor perda de peso. As variáveis estudadas no período pré cirúrgico não contribuíram de forma significativa para a perda de peso. Palavras-chave: Cirurgia Bariátrica; Comportamento Alimentar; Depressão; Diabetes Mellitus Tipo 2; Obesidade Mórbida. ABSTRACTIntroduction: Obesity is associated with a great number of complications, including type 2 diabetes mellitus and psychiatric pathology. Bariatric surgery is the best solution to weight loss and improvement of complications in morbid obese patients. This study aims to analyze the evolution of type 2 diabetes mellitus and psychopathologic variables before and after bariatric surgery and assess the importance of different variables in weight loss. Material and Methods: This is a longitudinal study, which evaluates 75 patients before and after bariatric surgery (47 -LAGBlaparoscopic adjustable gastric band; 19 -RYGB -Roux-en-Y gastric bypass; 9 -sleeve) with a follow-up time between 18 and 46 months. A clinical interview and self report questionnaires were applied -Eating Disorder Examination questionnaire -EDE-Q and Beck Depression Inventory -BDI. Results:Results show an improvement in type 2 diabetes mellitus after surgery (χ 2 (1) = 26.132, p < 0.001). There was not a significant improvement among psychiatric pathology when we controlled the analysis for the type of surgery. It was verified that type 2 diabetes mellitus, depression and eating disorders in post-operative period are associated with less weight loss. This model explains 27% of weight variance after surgery (R 2 = 0.265) and it is significant F (3.33) = 2.981, p = 0.038. Discussion: Type 2 diabetes mellitus, psychiatric pathology and eating disorders after surgery influenced weight loss. It was not clear in what way this relation was verified, neither the relation that these metabolic and psychological variables may have during the postoperative period. Conclusion: Type 2 diabetes mellitus improved after surgery. Type 2 diabetes mellitus, depression and eating disorders influenced weight loss in the postoperativ...

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“…5 Research has shown that a decrease in body weight of 10 kg can lead to improvements in the effects of comorbid conditions associated with obesity. 6 It is for this reason that bariatric surgery has proved to be an effective treatment with long-term results in terms of improving and resolving the problems associated with comorbid conditions in individuals with obesity. This surgery positively impacts on life expectancy.…”

Section: Introductionmentioning

confidence: 99%

“…A decrease of 10% of a patient's excess weight, therefore, has an impact on the quality of life of the patient. 6 In a cohort study, bariatric surgery decreased excess weight by 67.1%, with a significant reduction in the relative risk of cardiovascular disease, in the risk of endocrine, respiratory, and infectious problems, and in cancer related to obesity and psychiatric care. Additionally, bariatric surgery reduced the risk of mortality by 89% and produced a 71.6% improvement in quality of life.…”

Section: Introductionmentioning

confidence: 99%

Obesity-related Metabolic Comorbidities Remission in Postbariatric Surgery Patients

Dorado¹,

López²,

Martin³

2017

WJOLS

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Impact of Bariatric Surgery on Comorbidities

Cited by 52 publications

References 145 publications

Do We Need A Wider Therapeutic Paradigm For Heart Failure With Comorbidities?: A Remote Australian Perspective

Do We Need A Wider Therapeutic Paradigm For Heart Failure With Comorbidities?: A Remote Australian Perspective

Diabetes Mellitus Tipo 2, Depressão e Alterações do Comportamento Alimentar em Doentes Submetidos a Cirurgia Bariátrica

Obesity-related Metabolic Comorbidities Remission in Postbariatric Surgery Patients

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