Impact of autonomic and self-regulation on cancer-related fatigue and distress in breast cancer patients – a prospective observational study

Abstract

AR seems to be a prognostic factor in breast cancer survivors, capable of reducing cancer-related fatigue and self-regulation distress as well. Further research is necessary in order to show how aR can be improved by therapeutic interventions.

Impact of a combined multimodal-aerobic and multimodal intervention compared to standard aerobic treatment in breast cancer survivors with chronic cancer-related fatigue - results of a three-armed pragmatic trial in a comprehensive cohort design

“…Sleep disorders, particularly insomnia, psychological distress or further chronic internal medical conditions constitute modulating and aggravating factors [4]. In 34% of breast cancer survivors CRF persists after 5 to 10 years [5], and global and cognitive fatigue are still captured after 10.6 years in 17 and 28% of patients, respectively [6]. In this population CRF is a frequent reason for invalidity pensions in Germany [7].…”

From Theory to Practice: Application of Self-Regulation Model for the Management of Fatigue among Cancer Patients Receiving Chemotherapy

“…Results from this study showed that theory-based intervention using the SRM directly enhanced affective and cognitive fatigue among cancer patients receiving chemotherapy. Earlier studies also showed that autonomic and self-regulation intervention have an independent impact on global and cognitive fatigue, self-regulation, and reduced anxiety and depression among breast cancer patients (24) . Educational programs on self-care regulation for patients with colorectal cancer who are receiving chemotherapy was also effective in reducing the intensity of symptoms such as nausea and vomiting (25) .…”

Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancer-related fatigue?

“…; Kröz et al . )], there is an increasing interest in multimodal therapy approaches (Reif et al . ).…”

“…Due to the severity of CRF symptoms and the only small to moderate effects of individual therapies as well as the increasing evidence of a high incidence of long-term and cognitive CRF [17-34 per cent and 31 per cent of breast cancer patients after 5-10 years, respectively (Bower et al 2006;Kröz et al 2014)], there is an increasing interest in multimodal therapy approaches (Reif et al 2010). This trend is further reinforced by growing evidence that AT alone appears to be insufficient for the treatment of cognitive fatigue (Dimeo et al 2008).…”

“…For this, we selected various questionnaires: the quality of life functional scales of the European Organization of Research and Treatment Health-Related Quality of Life Core Questionnaire (EORTC QLQ-C30) (Aaronson et al 1993) for which a slight but significant prognostic impact on survival has already been found in a meta-analysis (Quinten et al 2009); the Pittsburgh Sleep Quality Index (PSQI), a standard questionnaire on sleep quality (Buysse et al 1989) for assessing the influence of sleep quality on CRF (Savard et al 2005); and other questionnaires such as the scale of autonomic regulation scale (aR) (Kröz et al 2008a) and questionnaire-based methods for capturing the patients' adaptive capabilities and their coherence, the Self-Regulation Scale (SRS) (Grossarth-Maticek 1999) and the Internal Coherence Scale (ICS) ). In oncological outcome studies which used the questionnaires of aR, self-regulation and measures capturing coherence, the authors discussed these scales and concepts as useful to predict CRF and survival Gotay et al 2004;Kröz et al 2014).…”