Impact of Adjuvant Hormone Therapy on Sleep, Physical Activity, and Quality of Life in Premenopausal Breast Cancer: 12-Month Observational Study

Yeo, Seung Mi; Lim, Ji Young; Kim, Seok Won; Chae, Byung Joo; Yu, Jonghan; Ryu, Jai Min; Hwang, Ji Hye

doi:10.4048/jbc.2023.26.e11

Cited by 2 publications

(2 citation statements)

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“…In addition, symptom burden changes accordingly at different time points in treatment. Symptoms worsened consistently from the start of OFS treatment to 6 months and were the worst or worsened fastest around 6 months [ 9 , 18 ]. Finally, Bubis et al pointed out that due to the corresponding symptom burden that occurs at the early stages of cancer treatment, it is necessary to give patients some guidance at an early stage to reduce their symptom burden [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

“…In addition, the long duration of treatment (the standard course is 5 years) and the high-frequency treatments (one injection every 28 days in the hospital) also add to their physical and psychological burden [5]. Yeo et al showed that OFS-treated patients had significantly higher severity of hot flashes than non-OFS-treated breast cancer patients [9]. Also compared to the latter, OFS-treated patients had significantly higher incidence of depression, hot flashes, and osteoporosis where the odds ratio (OR) was 2.76 (95% confidence interval (CI): 1.04 -7.37), relative risk was 2.14 (95% CI: 1.01 -4.51), and relative risk was 1.66 (95% CI: 1.10 -2.50), respectively [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

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Empowerment-Led Guided Self-Help Intervention for Symptom Burden in Breast Cancer Women Treated With Ovarian Function Suppression: A Randomized Trial Protocol

Li,

Chen,

Wang

et al. 2024

World J Oncol

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Background Ovarian function suppression (OFS) treatment causes breast cancer patients’ estrogens to fall rapidly to postmenopausal levels, and the 5-year treatment duration and 28-day treatment cycles place a heavy physical and psychological symptom burden on them, which in turn directly or indirectly affects the survival benefit. Managing symptom burden early in treatment is critical, but OFS-related studies have yet to be seen. Self-management is essential for patients’ symptom burden. However, self-help management is hampered by patients’ lack of knowledge, skills, motivation, etc. Guided self-help intervention (GSH) provides a feasible approach. Empowerment theory is a promising theoretical framework to guide self-management. Methods A prospective two-arm parallel randomized controlled single-blind clinical trial will be conducted to investigate the effect of symptom burden GSH based on empowerment theory in breast cancer patients in the early stages of OFS treatment. A block randomization method is used to allocate 144 patients to either the control or intervention group. The program is conducted according to the OFS return-to-hospital treatment cycle. The intervention group will receive a total of two rounds and five sessions of empowering GSH, lasting at least 15 weeks in total; the control group will receive only usual nursing care. Symptom burden and related metrics will be assessed at baseline and 1, 3, and 6 months after OFS treatment, and changes between and within groups will be explored. This paper adhered to the SPIRIT and CONSORT guidelines. Conclusion These results will help to validate the GSH in symptom burden management for breast cancer patients in OFS treatment early stages. It enriches its symptom burden management research and may provide implications for the whole cycle of OFS treatment patients.

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Section: Introductionmentioning

confidence: 99%