Immunotherapy for Allergic Disease

Matsui, Elizabeth C.; Eggleston, Peyton A.

doi:10.1016/b978-1-4377-0271-2.00027-4

Cited by 1 publication

(1 citation statement)

References 53 publications

(37 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In 2002, Patterson's Allergic Disease reported that large LRs were a cause for concern, dosages should be reduced or repeated, and maintenance dosages should be lowered [17]. The 2003 edition of Pediatric Allergy: Principles and Practice recommended a dose repeat when the previous dose produced local swelling greater than 3 cm (the size of a silver dollar), and a twofold drop with local swelling of 5 cm or more [18]. Finally, the 2003 SCIT practice parameters recommended careful evaluation of any patient with a late LR more than 30 min after the SCIT injection as an action to reduce the risk of anaphylaxis [19].…”

Section: Current Local Reaction Literature and Recommendationsmentioning

confidence: 99%

How Should Allergists Deal With Local Reactions to Allergen Immunotherapy?

Tankersley

2010

Curr Allergy Asthma Rep

View full text Add to dashboard Cite

Despite the well-known benefits of subcutaneous immunotherapy (SCIT), adverse reactions include both local reactions (LRs) and systemic reactions. An LR is a well-known adverse event associated with SCIT injections and is defined as any swelling located at or near the injection site following allergen injection. Concerns that LRs might predict systemic reactions have historically motivated allergists to dose adjust for LRs. More recent data have dispelled this notion, although many allergists continue to dose adjust for other reasons. This article discusses the historical response to LRs and dose adjustments and reviews the most recent literature addressing LRs to SCIT. Treatment options, although they are either unproven or not studied, are offered as an alternative to routine dose adjustments for LRs. Education remains the foundation of physician-patient communication concerning LRs.

show abstract

Section: Current Local Reaction Literature and Recommendationsmentioning

confidence: 99%

How Should Allergists Deal With Local Reactions to Allergen Immunotherapy?

Tankersley

2010

Curr Allergy Asthma Rep

View full text Add to dashboard Cite

show abstract

Immunotherapy for Allergic Disease

Cited by 1 publication

References 53 publications

How Should Allergists Deal With Local Reactions to Allergen Immunotherapy?

How Should Allergists Deal With Local Reactions to Allergen Immunotherapy?

Contact Info

Product

Resources

About