Immunotargeting of Melanoma

Long-term survival of high-risk melanoma patients immunized with a Hyper-IL-6-modified allogeneic whole-cell vaccine after complete resection

“…Historically, renewed interest was observed in early 1980s when tumor cells started to be used as a basis for the formulation of therapeutic vaccines [13]. Melanoma was one of the major targets for this type of active immunotherapy approaches.…”

“…Thus, post-operative, systemic, non-toxic adjuvant therapies are critically required [12]. A number of randomized clinical trials of systemic active adjuvant immunotherapy following high-risk melanoma resection have failed to demonstrate the extension of OS [1,7,12,13].…”

Cromosomas Y Citogenética De Helmintos (Turbellaria, Trematoda, Cestoda, Nematodayacanthocephala)

“…When one turns to the Platyhelminthes, one finds a somewhat similar picture, although this phylum is far less homogeneous than the Nematoda, with such variant groups as the non-parasitic Turbellaria and the parasitic Trematoda and Cestoda. groups remain only partially resolved (Kodedova et al, 2000;Mackiewicz, 1981Mackiewicz, , 1982Mackiewicz, , 1994Mackiewicz, , 2003Olson et al, 2001Olson et al, , 2008Waeschenbach et al, 2007) Les caryotypes de trois planaires marines nord-americaines: contribution a la phylogenie et a la c l a s s i f i c a t i o n d u g r o u p e ( P l a t y h e l m i n t h e s , Tu r b e l l a r i a , Tricladida). Canadian Journal of Zoology,vol.…”

Cariotipo De Adenoscolex Oreini: Primer Dato Citogenético Del Orden Caryophyllidea (Cestoda) De Especies De Schizothorax Del Valle De Kashmir, India

“…Caryophyllids are unique among Eucestoda in having a monopleuroid body plan that is they have neither internal proglottidization nor external segmentation and have a single set of reproductive organs. The embryo has six hooks; scolex is highly variable, with acetabula, loculi, bothria, folds, fimbriae, terminal introvert or without special attachment structures (Mackiewicz, 1972(Mackiewicz, , 1994. They are intestinal parasites of cypriniform and siluriform freshwater fishes; intermediate hosts are aquatic annelids (Mackiewicz, 1982).…”