Immunosuppression in Dogs Naturally Infected with Babesia gibsoni.

Molecular Evidence of Infections withBabesia gibsoniParasites in Japan and Evaluation of the Diagnostic Potential of a Loop-Mediated Isothermal Amplification Method

“…gibsoni infection has frequently been found in companion dogs, creating a clinical problem (2,8). The clinical severity of babesiosis in dogs is influenced to an extent by the age and the immune status of the affected individual: B. gibsoni infection causes progressive anemia in infected animals after surgery or when the animals are receiving immunosuppressive therapy and in general tends to be more severe in young dogs, with a subclinical carrier state arising after recovery from infection.…”

High-Level Expression of Truncated Surface Antigen P50 of Babesia gibsoni in Insect Cells by Baculovirus and Evaluation of Its Immunogenicity and Antigenicity

“…B. gibsoni infection is endemic in many regions of Asia, Africa, Europe, and America (11,14). Recently, this disease has frequently been observed in companion animals, becoming a significant problem from a clinical point of view (1,4,16,20).…”

Identification and Expression of a 50-Kilodalton Surface Antigen of Babesia gibsoni and Evaluation of Its Diagnostic Potential in an Enzyme-Linked Immunosorbent Assay

“…B. gibsoni infection is endemic in many regions of Asia, Africa, Europe, and the Americas (7,21,25). Recently, this disease has been found to occur frequently in companion animals and has become a big problem clinically (4,10). In chronically infected dogs, the disease recurs and causes advanced anemia after an operation or while a dog is on immunosuppressive therapy.…”