Immunomodulatory biomaterials against bacterial infections: Progress, challenges, and future perspectives

Emerging contaminants: A One Health perspective

“…The intricate interplay between pathogenic bacteria and various environmental sources, particularly in agricultural settings, underscores the complexity of this challenge. 241 , 242 Agricultural soils are often underestimated as reservoirs of human and animal pathogens and can give rise to a spectrum of diseases affecting air, water, and food. 243 For example, bacterial species such as Bacillus anthracis , Vibrio cholera , and Burkholderia pseudomallei have the potential to cause severe infection and, in some cases, death through direct contact.…”

“…PPCPs (e.g., antibacterial creams and ointments), when improperly used, disposed of, or inadequately treated, could contribute to the development of ARBs. 242 , 460 , 461 This outcome poses a significant threat to public health as conventional treatments become less effective, leading to an increased prevalence of infectious diseases. 461 For example, symptoms of infectious diseases, particularly those related to airway infections (e.g., lung infections), were much more common among individuals with compromised health or chronic conditions who used antibacterial medications.…”

Shining light on carbon dots: Toward enhanced antibacterial activity for biofilm disruption

“…[7] Furthermore, by 2050, antibiotic-resistant bacterial infections were estimated to annually cause up to 10 million deaths worldwide, and a loss of over 3.8% of the global gross domestic product. [8,9] Nanostructured materials have gained popularity in the postantibiotic era, due to their associated unique properties. [9,10] It has been recognized that nanomaterials hardly cause antibiotic resistance while exhibiting long-lasting antibacterial activity.…”

“…[ 7 ] Furthermore, by 2050, antibiotic‐resistant bacterial infections were estimated to annually cause up to 10 million deaths worldwide, and a loss of over 3.8% of the global gross domestic product. [ 8,9 ]…”

Polydopamine Nanocarriers with Cascade-Activated Nitric Oxide Release Combined Photothermal Activity for the Therapy of Drug-Resistant Bacterial Infections

“…Among them, calcium peroxide nanoparticles have been extensively investigated for antibacterial applications because of their low toxicity and easy operation. , CaO 2 exhibits relative stability when dry, but gradually decomposes when comes in contact with water . CaO 2 has recently garnered attention in cancer therapy because of its ability to degrade within an acidic microenvironment, thereby facilitating H 2 O 2 liberation. , The bacterial biofilm microenvironment is similar to the tumor microenvironment, including a significantly lower pH than surrounding tissues. , Consequently, introducing CaO 2 nanoparticles allows for autonomous H 2 O 2 production during treatment.…”