Immunomodulatory and Anti-Inflammatory Activity of Mulberry (Morus alba) Leaves Fermented with Hericium erinaceum Mycelium by Solid-State Culture

김훈,; 정재현,; 신지영,; 김동구,; 유광원,

doi:10.3746/jkfn.2011.40.9.1333

Cited by 7 publications

(2 citation statements)

References 20 publications

(4 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It remains unclear whether the observed effects are due to scoparone, its biotransformation products, or the genuine fungal metabolites. The same holds true for a study where a solid culture of H. erinaceus cultivated with Morus alba (white mulberry) was found to have anti-inflammatory activity, but no detailed analytical characterization was carried out (Kim et al 2011a).…”

Section: Numerous Types Of Biologically Active Compounds From Mushroo...mentioning

confidence: 67%

Hericium erinaceus, an amazing medicinal mushroom

et al. 2015

View full text Add to dashboard Cite

Medicinal mushrooms have become a compelling topic because the bioactive compounds they contain promise a plethora of therapeutic properties. Hericium erinaceus commonly known as "Houtou" or "Shishigashira" in China and "Yamabushitake" in Japan, has commonly been prescribed in Traditional Chinese Medicine (TCM), because its consumption has been shown to be beneficial to human health. The species is found throughout the northern hemisphere in Europe, Asia, and North America. Hericium erinaceus has been firmly established as an important medicinal mushroom and its numerous bioactive compounds have been developed into food supplements and alternative medicines. However, the correspondence of the active components that cause the observed effects is often not clear. The mushroom as well as the fermented mycelia have been reported to produce several classes of bioactive molecules, including polysaccharides, proteins, lectins, phenols, and terpenoids. Most interestingly, two classes of terpenoid compounds, hericenones and erinacines, from fruiting bodies and cultured mycelia, respectively, have been found to stimulate nerve growth factor (NGF) synthesis. In this review we examine the scientific literature to explore and highlight the scientific facts concerning medicinal properties of H. erinaceus. We provide up-to-date information on this mushroom, including its taxonomy and a summary of bioactive compounds that appear related to the therapeutic potential of H. erinaceus.

show abstract

Section: Numerous Types Of Biologically Active Compounds From Mushroo...mentioning

confidence: 67%

Hericium erinaceus, an amazing medicinal mushroom

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Recently, the study of the physiological activities, including antioxidant activity and immune activation, of liquid mycelium cultures has progressed steadily (5). In addition, mycelium fermentation with natural products has the advantage of being able to utilize all of the useful natural components of the mycelium (5).…”

Section: Introductionmentioning

confidence: 99%

Anti-obesity effect of robusta fermented with Leuconostoc mesenteroides in high-fat diet-induced obese mice

Choi

Ryu

Park

et al. 2017

Experimental and Therapeutic Medicine

Self Cite

View full text Add to dashboard Cite

Abstract. Robusta beans cultivated with Monascus ruber (RMR) were successively fermented with Leuconostoc mesenteroides (LM) and the antiobesity effects were examined. To produce an obese mouse model to investigate the hypolipidemic effects, ICR mice were fed the same high-fat diet for 6 weeks. Treatment groups were given 10 or 20% RMR-LM. Body weight changes in the 20% RMR-LM group were lower compared with those in the control group. Visceral adipose tissue weight and adipose size were significantly lower in the 20% RMR-LM group compared with those in the control group. Significant improvement in glucose tolerance was observed in the 10 and 20% RMR-LM groups compared with the control group. The 20% RMR-LM group exhibited a significant reduction in serum glucose concentration. Hepatic mRNA levels of sterol regulatory element-binding protein 1, fas cell surface death receptor, and peroxisome proliferator-activated receptor γ, which are associated with lipid, and fatty acid metabolism, in the 20% RMR-LM group were significantly lower compared with those in the control group. The results of the present study demonstrated that 20% RMR-LM may be used to prevent obesity, and ameliorate diabetes and lipid metabolism imbalances.

show abstract

Evaluation of acute toxicity, genotoxicity and inhibitory effect on acute inflammation of an ethanol extract of Morus alba L. (Moraceae) in mice

Oliveira

Nascimento

Ferreira

et al. 2016

Journal of Ethnopharmacology

View full text Add to dashboard Cite

The ethanol extract from M. alba leaves administered intraperitoneally possesses a greater degree of toxicity in mice when compared to per os administration. The extract was not genotoxic when ingested by mice and exhibited a highly inhibitory effect against acute inflammation, which is probably linked to the presence of chlorogenic acid and flavonoids in the composition. This work contributes to the determination of safety of the medicinal use of M. alba leaves.

show abstract

Immunomodulatory and Anti-Inflammatory Activity of Mulberry (Morus alba) Leaves Fermented with Hericium erinaceum Mycelium by Solid-State Culture

Cited by 7 publications

References 20 publications

Hericium erinaceus, an amazing medicinal mushroom

Hericium erinaceus, an amazing medicinal mushroom

Anti-obesity effect of robusta fermented with Leuconostoc mesenteroides in high-fat diet-induced obese mice

Evaluation of acute toxicity, genotoxicity and inhibitory effect on acute inflammation of an ethanol extract of Morus alba L. (Moraceae) in mice

Contact Info

Product

Resources

About