1988
DOI: 10.1016/0378-8741(88)90145-6
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Immunomodulation by a unicellular green algae (Chlorella pyrenoidosa) in tumor-bearing mice

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Cited by 37 publications
(25 citation statements)
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“…The beneficial effects of Chlorella preparations include improvement of immune function and a better control of ulcerative colitis and hypertension [6,7]. Chlorella preparations associated with the prevention and treatment of cancer, bacterial, fungal and viral infections appear to be mediated via the immune system rather than its direct toxicity against the tumor or pathogen [8][9][10][11][12][13][14][15][16][17]. An aqueous extract of Chlorella pyrenoidosa (CP) 1 (Respondink; Ocean Nutrition Canada, Halifax, NS, Canada) has recently been shown to be safe and to enhance the antibody response in subjects receiving influenza vaccination [18].…”
Section: Introductionmentioning
confidence: 99%
“…The beneficial effects of Chlorella preparations include improvement of immune function and a better control of ulcerative colitis and hypertension [6,7]. Chlorella preparations associated with the prevention and treatment of cancer, bacterial, fungal and viral infections appear to be mediated via the immune system rather than its direct toxicity against the tumor or pathogen [8][9][10][11][12][13][14][15][16][17]. An aqueous extract of Chlorella pyrenoidosa (CP) 1 (Respondink; Ocean Nutrition Canada, Halifax, NS, Canada) has recently been shown to be safe and to enhance the antibody response in subjects receiving influenza vaccination [18].…”
Section: Introductionmentioning
confidence: 99%
“…Estimates of the CGF content in raw Chlorella pyrenoidosa is approximately 5%. A number of scientific reports from Japan have shown that broken cell wall preparations and extracts of Chlorella pyrenoidosa and other Chlorella species when either given orally or injected promote growth and healing, stimulates the immune system such that the host is protected from infection, and exerts significant anti-cancer activity (Konishi et al, 1985;Yamaguchi et al, 1985;Komiyama et al, 1986;Tanaka et al, 1986;Miyazawa et al, 1988;Merchant et al, 1990).…”
Section: Introductionmentioning
confidence: 97%
“…doi:10.1016/j.intimp.2004. 11.015 malignant diseases [1][2][3]. The increased interest in new approaches to the immunotherapy of cancer and a considerable demand for therapeutic agents which can modulate the several forms of immunodeficiency has encouraged studies on the immunomodulatory mechanism of natural and synthetic substances [4][5][6][7].…”
Section: Introductionmentioning
confidence: 99%