Immunology of Candidiasis

Wilton, James; Lehner, Thomas

doi:10.1007/978-1-4684-1009-9_21

Cited by 9 publications

(10 citation statements)

References 286 publications

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“…Wilton and Lehner (1980) reported that both mucocutaneous and systemic candidosis are typically associated with defects in the cell-mediated immune response. These can be caused by deliberate immunosuppression (as in transplant patients) or in cancer patients treated with cytotoxic drugs; they can be associated with some underlying disease, such as the human immunodeficiency virus (HIV) infection, or they may reflect specific deficiencies in the cell-mediated immune response, as in chronic mucocutaneous candidosis (Kirkpatrick, 1988 (Lindquist and Craig, 1988).…”

Section: Humoral Immunitymentioning

confidence: 99%

“…Joynson et al (1972) demonstrated impaired cell-mediated immunity to C. albicans in iron-deficient subjects both in vivo and in vitro, which were restored once the iron levels returned to normal. Other general effects of iron deficiency that may bear a relationship to oral candidosis include deficient phagocytosis and antibody production (Wilton and Lehner, 1981).…”

Section: Dietary Factorsmentioning

confidence: 99%

See 1 more Smart Citation

Candida and Oral Candidosis: A Review

Scully

Elkabir

Samaranayake

1994

Critical Reviews in Oral Biology & Medicine

311

245

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Candida species are the most common fungal pathogens isolated from the oral cavity. Their oral existence both as a commensal and an opportunist pathogen has intrigued clinicians and scientists for many decades, and recent investigations have revealed many attributes of this fungus contributing to its pathogenicity. In addition, the advent of the human immunodeficiency virus infection and AIDS has resulted in a resurgence of oral Candida infections. Clinicians are witnessing not only classic forms of the diseases but also newer clinical variants such as erythematous candidosis, rarely described hithertofore. Therefore, this review is an attempt at detailing the current knowledge on Candida and oral candidoses together with the newer therapeutic regimes employed in treating these mycoses.

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Section: Humoral Immunitymentioning

confidence: 99%

Section: Dietary Factorsmentioning

confidence: 99%

Candida and Oral Candidosis: A Review

Scully

Elkabir

Samaranayake

1994

Critical Reviews in Oral Biology & Medicine

311

245

View full text Add to dashboard Cite

show abstract

“…57 Other general effects of iron deficiency may include impaired phagocytosis and inadequate antibody production. 58,59 The association between oral candidiasis and iron deficiency was first described by Cawson. 60 A high prevalence of candidal infection in iron-deficient patients with angular cheilitis and atrophic glossitis has also been reported.…”

Section: Iron Deficiencymentioning

confidence: 99%

Host factors affecting oral candidiasis

Wyk

Steenkamp

2011

Southern African Journal of Epidemiology and Infection

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Review: Host factors affecting oral candidiasis Candida species are responsible for a wide range of systemic as well as superficial opportunistic infections, which are of particular importance among debilitated and immunocompromised patients. Species of the genus Candida comprise part of the oral commensal microflora of healthy individuals, with Candida albicans being the most common pathogen of the genus. A diverse array of host factors has been implicated in the pathogenesis of oral candidiasis. This paper describes the local, systemic and iatrogenic factors affecting oral candidiasis.Peer reviewed.

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“…From a clinical standpoint, there is abundant inferential evidence that both mucocutaneous and systemic candidiasis are typically associated with defects or weaknesses in the cellmediated immune response (12). These can be caused by deliberate immunosuppression, for example in transplant patients, or in cancer patients treated with cytotoxic drugs; they can be associated with some underlying disease, such as human immunodeficiency virus (HIV) infection; or they may reflect specific deficiencies in the cell-mediated immune response, as in chronic vaginal candidiasis (61,62) or chronic mucocutaneous candidiasis (63).…”

Section: Immunological Responses To Infectionmentioning

confidence: 99%

“…1,11,12) and it is not intended to reiterate all of that material here. Instead, the objective of this paper is to review critically recent research on the antigens of C. albicans, the immune responses elicited by them, and how these findings have contributed to an understanding of the mechanisms underlying host susceptibility and resistance.…”

Section: Introductionmentioning

confidence: 99%