“…Low serum levels of IgA were most often described (Sorrell et al, 1971;Grob and Herold, 1972;Slavin et al, 1974;Aarli and Tonder, 1975;Buckley, 1975;Seager et al, 1975;Aarli, 1976;Kanoh and Uchino, 1976;Masi et al, 1976;Andersen and Mosekilde, 1977). Immune reactions dependent on T-lymphocytes have also been shown to be abnormal in some epileptic patients as evidenced by absent delayed-type skin tests to various ubiquitous antigens, diminished lymphocyte stimulation by plant mitogens, and a decrease of circulating T cells (Sorrell et al, 1971;Massimo et al, 1976). There are still many questions to be answered, such as whether only certain forms or stages of epilepsy are associated with immunodeficiencies, or whether anticonvulsant drugs especially hydantoins, are mainly responsible for, or at least add to the genesis of, the immunity abnormalities.…”