Immunological development in infants of allergic parents

Abstract

Serum immunogiobulins were determined every 4 months from cord blood to age 2 years in ninety-two infants ofallergic parents. By 7 months of age, the concentration of IgA was significantly greater in infants who developed atopic dermatitis than those who did not. The IgA was also significantly greater than in matched non-allergic controls. The dilTerence continued to the end of the 2-year study. No significant difference was found in the three groups for levels of IgG and IgM. These findings dilTer from the results of a previous report and possible explanations are presented.

A Modern Clinical Approach to Food Hypersensitivity

“…The enthusiasm of some clinicians and experimental investigators for the prospects of prevention of food hypersensitivity by deferral of introduction of food other than the mothers' milk into the diet until late in infancy (70,78) has not been shared by others (34,79,80). Uncertain at present is whether sensitization to foods may be prevented in this way or (jnly deferred until the foods are ultimately added to the diet.…”