Immunohistochemical localization of 3β-Hydroxysteroid dehydrogenase and progesterone receptors in the ovary and placenta during gestation of the placentotrophic lizard Mabuya sp (Squamata: Scincidae)

Duarte-Méndez, Melissa; Quintero-Silva, Jennifer; Ramírez‐Pinilla, Martha Patricia

doi:10.1016/j.ygcen.2018.02.017

Cited by 5 publications

(1 citation statement)

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“…In reptiles, both isoforms have been reported and are associated with the stage of the reproductive cycle (Custodia-Lora and Callard, 2002;Biazik et al, 2012;Hammouche et al, 2012;Motta et al, 2020). During follicular development, PR could stimulate the proliferation in the germinal beds, recruitment, and transition to the primary oocyte (Custodia-Lora and Callard, 2002;Jones, 2011;Holding et al, 2014;Ramírez-Pinilla et al, 2015;Duarte-Méndez et al, 2018;Motta et al, 2020). As the follicular development progressed, we observed an increase in immunolabelling intensity.…”

Section: Discussionsupporting

confidence: 52%

Sex steroid receptors in the ovarian follicles of the lizard Sceloporus torquatus

Cruz-Cano

Sánchez-Rivera

Álvarez-Rodríguez

et al. 2023

Zygote

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Summary Estradiol and progesterone have been recognized as important mediators of reproductive events in the female mainly via binding to their receptors. This study aimed to characterize the immunolocalization of the estrogen receptor alfa (ERα), estrogen receptor beta (ERβ) and progesterone receptor (PR) in the ovarian follicles of the lizard Sceloporus torquatus. The localization of steroid receptors has a spatio-temporal pattern that depends on the stage of follicular development. The immunostaining intensity of the three receptors was high in the pyriform cells and the cortex of the oocyte of previtellogenic follicles. During the vitellogenic phase, the granulosa and theca immunostaining was intense even with the modification of the follicular layer. In the preovulatory follicles, the receptors were found in yolk and additionally, ERα was also located in the theca. These observations suggest a role for sex steroids in regulating follicular development in lizards, like other vertebrates.

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