Immunohistochemical identification and crossreactions of amyloid-A fibril protein in man and eleven other species

Immunohistochemical distribution of Amyloid Deposits in 25 Cows Diagnosed with Systemic AA Amyloidosis

“…The AA form of amyloid is derived from an acute-phase protein called serum amyloid A (SAA) that normally plays a role in cholesterol transport [9] and as a chemoattractant in the inflammatory process [2]. AA amyloid is the most frequently found amyloid in animals [7,10,17]. When the blood concentration of SAA is increased, typically as a result of chronic inflammation, certain isoforms of SAA are partially cleaved into fragments that have an increased propensity to form fibrillar aggregates (amyloid).…”

Increasing fatal AA amyloidosis in hunting falcons and how to identify the risk: a report from the United Arab Emirates

“…The antibodies applied were murine monoclonal mc1 (also available from Dako) and mc29 (known to cross-react with most species) directed against human AA [37] and three polyclonal rabbit antibodies directed against human and bovine AA [32], and against murine AA [7]. Included was also a rabbit anti-human ALl (HAR) antibody known to cross-react with ALl amyloid of humans, canines, felines, and equines [39][40][41].…”

“…In general, this disease is the result of longlasting inflammations in humans [2][3][4][5] and in animal species [6][7][8][9][10].…”

Familial Amyloid Polyneuropathy: Report of an Autopsy Case with Neuropathy, Vitreous Opacities and Polycystic Kidney

“…An unfixed part of the second biopsy was processed for serial frozen sections; some sections were stained with cresyl violet and the rest with antiserum against human prealbumin (Calbiochem Behring), using an indirect immunoperoxidase (PAP) method per formed as already described [Stemberger, 1979;Linke, 1982 Specimens o f cranial nerves, heart, kidney, gastrointestinal wall and skin were fixed in Kamovsky fluid and processed for electron microscopy.…”