Immunofluorescence-microscopy in measles

Abstract

Abstract. In 79 children who contracted measles the attempt was made to find the virus in epithelium cells of a buccal smear at different stages of the disease by the help of immunofluorescence. In 42 children (52O/o) this was successful. The test was always positive during the prodromal phase, frequently positive during the first and second day of the rash, but from the fifth day on no virus could be detected any more. In children who fell ill otherwise the test was invariably negative. It is suggested that immunofluorescence-microscopy is a rapid and reliable method for the establishment of the diagnosis of measles during the prodromal phase.

Untersuchungen zur Wertigkeit serologischer Befunde bei der Mononucleosis infectiosa*

“…EBV-Antikörperbestimmung. Die EBV-IgG-Antikörper bestimmten wir mit Hilfe der indirekten Immunfluoreszenz-Methode nach Henle, wie früher beschrieben (4). Hierzu werden Zellausstrichë von EBV-haltigen Burkitt-Lymphomkulturen mit dem Patientenserum in geometrischen Verdünnungen beschickt.…”