Immunity and effect of clopidol/methyl benzoquate and robenidine before and after weaning on rabbit coccidiosis in the field

Peeters, Jan; Geeroms, R.; Varewyck, H.; Bouquet, Y.; Lampo, P.; Halen, P.

doi:10.1016/s0034-5288(18)32181-7

Cited by 9 publications

(2 citation statements)

References 4 publications

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“…Many factors may affect the sensitivity of parasites to drug treatment. Previous exposures to other drugs and long-term use of the same drug could induce drug resistance ( 25 , 26 ). Coccidia in different regions or locations can also have different susceptibily to drug treatment ( 27 , 28 ).…”

Section: Discussionmentioning

confidence: 99%

Study on the pathogenicity, immunogenicity, endogenous development and drug sensitivity of Eimeria kongi

Fang

Shi²,

Wang³

et al. 2023

Front. Vet. Sci.

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Following the discovery of Eimeria kongi, we investigated the pathogenicity, immunogenicity, endogenous development and drug sensitivity of this coccidian. Coccidia-free rabbits were inoculated with 1 × 102 to 5 × 104 sporulated oocysts of E. kongi before challenge 14 days post inoculation. E. kongi was moderately pathogenic and induced good immunity against re-infection. All inoculated doses results in reduced food intake and body weight gain, and an inoculation oocyst dose of 1 × 103 or higher caused various degrees of diarrhea. Except for one death of the highest dose group, all rabbits recovered 12 days post inoculation. An inoculation dose of 1 × 103 or 1 × 104 oocysts conferred the most effective protection from re-infection, which reduced oocyst output by approximately 99% and maintained body weight gain. Four generations of schizogony were observed, and the endogenous development mainly occurred in the jejunum and ileum of rabbits. E. kongi was most sensitive to sulfachloropyrazine sodium, followed by decoquinate; it is resistant to diclazuril. Both decoquinate and sulfachloropyrazine sodium may be effective in the control of E. kongi infection.

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Section: Discussionmentioning

confidence: 99%

Study on the pathogenicity, immunogenicity, endogenous development and drug sensitivity of Eimeria kongi

Fang

Shi²,

Wang³

et al. 2023

Front. Vet. Sci.

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“…Both Stodart (1968) and Cowan (1983) suggested that coccidiosis might be a major cause of mortality in young rabbits, although it appears that the intensity of infection is greatest when rabbits weigh between 500-1000 g (Boag, 1989). Laboratory experiments have also indicated that until kittens weigh about 500 g they have some resistance to infection, which is presumably maternal in origin (Durr & Pellerdy, 1969;Peeters et al, 1983).…”

Section: Discussionmentioning

confidence: 99%

Communications from the Mammal Society—No. 66

Gorman¹

1993

Journal of Zoology

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Eimeria sp. from the rabbit (Oryctolagus cuniculus): Pathogenicity and immunogenicity ofEimeria intestinalis

Coudert¹,

Licois²,

Provôt³

et al. 1993

Parasitol Res

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The pathogenicity and immunogenicity of Eimeria intestinalis was evaluated in SPF rabbits. The animals were given immunizing doses of 6, 6 x 10(2), 6 x 10(3), and 6 x 10(4) sporulated oocysts and were challenged with 3 x 10(3) oocysts. The criteria analysed were the daily weight gain and the oocyst output. This study showed that E. intestinalis had strong immunogenicity, as the inoculation of 6 oocysts was sufficient to minimize the clinical expression of the disease following the challenge and to reduce the oocyst output by about 60%. The immunity towards the excretion of oocysts and the illness was absolute in animals inoculated with 600 or more oocysts. Moreover, this protection seemed to be efficient at least 8 weeks after the challenge. The present results also confirm the pathogenicity of E. intestinalis, although the occurrence of diarrhoea may be irregular, and emphasize the fact that the capacity of this Eimeria for multiplication is not a criterion for clinical diagnosis of the disease.

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Immunity and effect of clopidol/methyl benzoquate and robenidine before and after weaning on rabbit coccidiosis in the field

Cited by 9 publications

References 4 publications

Study on the pathogenicity, immunogenicity, endogenous development and drug sensitivity of Eimeria kongi

Study on the pathogenicity, immunogenicity, endogenous development and drug sensitivity of Eimeria kongi

Communications from the Mammal Society—No. 66

Eimeria sp. from the rabbit (Oryctolagus cuniculus): Pathogenicity and immunogenicity ofEimeria intestinalis

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