Immune response of lambs experimentally infected with Haemonchus contortus and parenterally treated with a combination of zinc and copper

Schafer, Andressa S.; Leal, Marta L.R.; Molento, Marcelo Beltrão; Aires, Adelina Rodrigues; Duarte, Marta M.M.F.; Carvalho, Fabiano B.; Tonin, Alexandre Alberto; Schmidt, Lucas; Flores, Érico M.M.; França, Raqueli Teresinha; Grando, Thirssa H.; Minho, Alessandro Pelegrine; Krause, Alexandre; Antoniazzi, Alfredo Q.; Lopes, Sonia T.A.

doi:10.1016/j.smallrumres.2014.10.016

Cited by 22 publications

(21 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The findings of this study are also congruent with the results reported by Burke and Miller (2008) who observed no effect of dietary copper sulfate on the GI nematodes of goats. Likewise, Schafer et al (2015) also mentioned that supplementation of Cu and Se in sheep against H. contortus infection did not reduce EPG and worm number. On the contrary, reduced EPG have been observed in small ruminants treated with copper oxide wire particles (COWP) (Vatta et al, 2009;Soli et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

Correlation of Trace Mineral Profiles with Gastrointestinal Worm Burden in Rangeland Sheep of Chakwal District, Punjab, Pakistan

Qudoos¹,

Khan²,

Sajid³

et al. 2017

IJAB

View full text Add to dashboard Cite

To cite this paper: Qudoos, A., M.N. Khan, M.S. Sajid and G. Muhammad, 2017 Pearson correlation demonstrated a non-significant (p>0.05) correlation of trace and ultra-trace minerals with EPG magnitude in naturally parasitized sheep of the study area. In conclusion, trace and ultra-trace mineral levels in naturally infected sheep flocks exhibited no significant role in reducing GI parasitic burden.

show abstract

Section: Discussionmentioning

confidence: 99%

Correlation of Trace Mineral Profiles with Gastrointestinal Worm Burden in Rangeland Sheep of Chakwal District, Punjab, Pakistan

Qudoos¹,

Khan²,

Sajid³

et al. 2017

IJAB

View full text Add to dashboard Cite

show abstract

“…In group III, increased level of IgA and IgG were not statistically significant but the level of IgM was statistically significant (P<0.05) and IgE increased and statistically was significant (P<0.001). These finding resembles Schafer et al (2015). IgG and IgM are the major Igs which are responsible in the complement activation, opsonisation, neutralization of toxins (Shah et al 2011).…”

mentioning

confidence: 90%

The Effect of Used Immunostimulating Drugs with FMD Vaccine on Immunoglobulins in Sheep

Abdullah¹,

Başbuğan

2020

Van Veterinary Journal

View full text Add to dashboard Cite

In this study, the effect of used immunostimulating drugs with FMD vaccine on immunoglobulins was aimed to investigate in sheep. For this purpose 40 healthy sheep were divided into 4 groups. Blood and serum samples were taken from all animals from 0 days before the study. Blood samples were measured immediately, and IgA, IgG, IgM, IgE and Zn values from biochemical parameters were stored for measurement. Group I was applied only FMD vaccine, group II Levamisole with the FMD vaccine, group III Zinc with FMD vaccine and the last group IV AD3E was applied with FMD vaccine. After 21 days, blood and serum samples from all groups were taken again and hematologic and IgA, IgG, IgM, IgE and Zn values were compared according to the values of day 0. No statistical difference was found between the groups except for PLT in hematological parameters (p> 0, 05) when compared to pre-vaccination and post-vaccination. In groups II and III there was a significant increase in PLT levels. Biochemical analysis showed IgA, IgG, IgM and IgE levels to be higher in IgG (p <0, 05) and IgE (p <0,001) in groups II and III when levels compared to before vaccination. There were statistically significant increases in IgM (p <0.05) in group IV.

show abstract

“…While, Rizwan et al (2019) reported that sheep having high level of Zn and Cu in sera showed lower burden of GI parasites. Animals deficient in Co are less immune to parasites than animals having adequate amount of Co. Lambs having Co deficiency showed higher faecal egg counts, less immune response and lower vitamin B 12 production than the lambs provided with higher amount of Co (Schafer et al, 2015).…”

Section: Discussionmentioning

confidence: 85%

“…In another study, serum of experimentally infected sheep with T. colubriformis showed lower level of Zn (Symons, 1983). Schafer et al (2015) reported that higher level of Cu and Se in sheep did not show any reduction in burden of H. contortus.…”

Section: Discussionmentioning

confidence: 94%

Effect of Trace Element Supplementation on the Gastrointestinal Parasites of Grazing Sheep

2020

THE JAPS

View full text Add to dashboard Cite

Alternative gastrointestinal (GI) parasite control strategies including phytomineral/ trace-element supplementation have gained currency in preview of anthelmintic resistance in the grazing sheep. This paper reports an association of the selected plants/ forages having optimum levels of Zinc (Zn), Copper (Cu), Manganese (Mn) and Cobalt (Co) on the GI parasitic burden in sheep and hence on the productive performance of the grazing sheep of Multan district, Punjab, Pakistan. To this end, levels of trace elements were determined in the plants/ forages preferred by the grazing sheep, and in the sera of randomly selected grazing sheep (n =384). Serum trace element profile was correlated with the GI parasitic burden to determine the possible impact of trace-elements on GI parasitic load. After pre-treatment, wet digestion of sera and plants, concentration of the selected minerals (Cu, Co, Zn and Mn) were measured using spectrophotometry. Faecal samples (n=384) were subjected to the quantitative faecal examination using McMaster technique. Overall 42.44% prevalence of GI parasites was found in the study population. Of the eight screened forages, Cynodon dactylon, Launaea nudicaulis and Digitaria sanguinalis showed top three levels of Mn in decreasing order. Comparative mineral profile of sera was significantly different among the four tehsils (administrative units) of Multan district, Punjab, Pakistan. Mn showed significant correlation with the egg per gram (EPG) of faeces in sheep of tehsil Shujabad, whereas, Cu, Zn and Co showed insignificant results in all tehsils of Multan district. Further research is needed to explain the possible mechanism involved in the role of Mn in the indirect resilience of animals against the GI parasites. These forages might be preferred as holistic approach and possible use as a preventive management of GI parasitism in grazing sheep of the country.

show abstract

Immune response of lambs experimentally infected with Haemonchus contortus and parenterally treated with a combination of zinc and copper

Cited by 22 publications

References 17 publications

Correlation of Trace Mineral Profiles with Gastrointestinal Worm Burden in Rangeland Sheep of Chakwal District, Punjab, Pakistan

Correlation of Trace Mineral Profiles with Gastrointestinal Worm Burden in Rangeland Sheep of Chakwal District, Punjab, Pakistan

The Effect of Used Immunostimulating Drugs with FMD Vaccine on Immunoglobulins in Sheep

Effect of Trace Element Supplementation on the Gastrointestinal Parasites of Grazing Sheep

Contact Info

Product

Resources

About