2023
DOI: 10.3389/fcimb.2023.1215380
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Immune mechanisms in vulvodynia: key roles for mast cells and fibroblasts

Elena Tonc,
Gloriah K. Omwanda,
Kevin Arnold Tovar
et al.

Abstract: Vulvodynia is a debilitating condition characterized by painful sensitivity to touch and pressure in the vestibular tissue surrounding the vaginal opening. It is often a “diagnosis of exclusion” of idiopathic pain made in the absence of visible inflammation or injury. However, the association between increased vulvodynia risk and a history of yeast infections and skin allergies has led researchers to explore whether immune mechanisms of dysregulated inflammation might underlie the pathophysiology of this chron… Show more

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