Clinical Significance of Topical Spermidine Hyaluronate in Vestibulodynia: An Early Appraisal
Filippo Murina,
Carlo Ghisalberti
Abstract:Background: The most common subtype of chronic vulvar pain is provoked vestibulodynia. The entry of the vagina is the site of acute and recurrent pain in this highly prevalent and debilitating condition, which is characterized by pressure application or attempted vaginal penetration. The aim of this study was to determine the effectiveness of topical spermidine in patients with vestibulodynia. Methods: Topical gels containing spermidine in hyaluronate complexes Ubi1 and Ubi2 endowed with differentiated release… Show more
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