Immune Complex Uveitis: A Case

Ryan, Lawrence M.

doi:10.7326/0003-4819-88-1-62

Cited by 10 publications

(3 citation statements)

References 3 publications

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“…In contrast, his visual acuity improved immediately following the initiation of the rituximab and plasmapheresis he received for his type II essential cryoglobulinemia. This is consistent with reports of uveitis secondary to other types of cryoglobulinemia where ocular inflammation was unresponsive to topical steroids [2,4] and oral prednisone [2], with the case of type I cryoglobulinemia-associated uveitis also being subsequently responsive to rituximab and plasmapheresis therapy [2]. …”

Section: Discussionsupporting

confidence: 90%

“…Scleritis and peripheral ulcerative keratitis have been reported with hepatitis C-related type III cryoglobulinemia [3]. One case of anterior uveitis has also been reported in a patient with cutaneous vasculitis and an unspecified type of cryoglobulinemia [4]. We describe a patient with severe anterior uveitis secondary to type II essential cryoglobulinemia.…”

Section: Introductionmentioning

confidence: 94%

“…When no underlying condition is identified, the cryoglobulinemia is termed ‘essential’. Although cryoglobulinemia is primarily known to involve the joints, kidneys, and skin, a few cases of eye manifestations have been reported [2-4]. Type I cryoglobulinemia has been associated with moderate anterior uveitis and anterior segment ischemia [2].…”

Section: Introductionmentioning

confidence: 99%

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Anterior uveitis secondary to type II essential cryoglobulinemia

Nicholson

Sobrin

2013

J OPHTH INFLAMM INFECT

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BackgroundThe purpose of this report is to describe the association of severe anterior uveitis with type II essential cryoglobulinemia.FindingsA 40-year-old male with a history of psoriatic arthritis presented with severe anterior uveitis associated with type II essential cryoglobulinemia. His uveitis, refractory to steroid treatments, was well controlled following treatments for cryoglobulinemia. The temporal association between his cryoglobulinemia and uveitis, combined with his improved visual acuity and inflammation after plasmapheresis and rituximab infusions, suggests cryoglobulinemia to be the underlying condition of his uveitis.ConclusionsTo our best knowledge, this is the first reported case of anterior uveitis secondary to type II essential cryoglobulinemia.

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