Immune-awakening Saccharomyces-inspired nanocarrier for oral target delivery to lymph and tumors

Changes of postmortem apoptotic factors, genes and proteins and their potential associations with beef tenderization

“…The luminescence of each sample was measured using an Infinite M200 plate reader (TECAN, Switzerland). The ATP content was calculated by referring to the standard solution [17] .…”

Self-assembled nanomicelles for oral delivery of luteolin utilizing the intestinal lymphatic pathway to target pancreatic cancer

“…The intestinal lymphatic system (ILS) is an attractive biological pathway for providing intestinal absorption for medications administered through the oral route. 9 However, the presence of the ILS in the small intestine presents challenges in efficiently delivering drug vehicles bypassing the stomach environment. Enterocytes and microfold (M) cells play a crucial role in the transport of drugs through the ILS.…”

A novel fluoropolymer as a protein delivery vector with robust adjuvant effect for cancer immunotherapy

“…The carriers can protect antigen proteins against rapid elimination and degradation during the administration process, improving the bioavailability and immunogenicity of antigen proteins and triggering a robust immune response. 11–13 To date, various carriers have been applied, including metal–organic frameworks, 14 inorganic nanoparticles, 15 polymers, 16,17 liposomes, 18,19 hydrogels, 20,21 and DNA nanostructures, 22 among which polymers with the advantages of easy modification and good stability are one of the most promising candidates. Recently, fluoropolymers such as fluorinated dendrimers and polyethyleneimines (PEI) have been widely applied as nucleic acid and protein delivery vectors.…”