The global movement for racial justice and the rise of anti-Asian hate at the height of the pandemic have called new attention to race and racism in international politics. Although critical theorists have decried the “norm against noticing,” other scholars of international relations have long sidestepped the possible role of race in shaping contemporary international affairs. New studies of hierarchy in international relations open the door for new understandings of race in world politics. We propose an analytic framework for the relationship between racial hierarchy, international law, and foreign policy, demonstrating that race can help explain patterns of interstate interactions that sustain an unequal global order. Positing two faces of racism in international relations, we examine how race biases international law in practice and affects the assessment of foreign threats and national interest. We discuss key methodological challenges in empirical research on race in international relations, focusing on issues of measurement, aggregation, and causation. Expected final online publication date for the Annual Review of Political Science, Volume 25 is May 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.