Immediate skin responses to laser and light treatments

Wanner, Molly; Sakamoto, Fumio; Avram, Mathew M.; Anderson, R. Rox

doi:10.1016/j.jaad.2015.06.025

Cited by 21 publications

(21 citation statements)

References 91 publications

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“…The major negative outcome of laser treatment is early tissue reactions occurring immediately after laser treatment, which provide a reliable indication of tissue injury. Wanner et al reported that IEL is an indicator of laser-tissue reaction and PIH is caused by inflammation [4,19]. Thus, the occurrence of immediate-onset laser-tissue reaction is a strong indicator of the possibility of PIH [4,19].…”

Section: Discussionmentioning

confidence: 99%

“…Wanner et al reported that IEL is an indicator of laser-tissue reaction and PIH is caused by inflammation [4,19]. Thus, the occurrence of immediate-onset laser-tissue reaction is a strong indicator of the possibility of PIH [4,19]. A similar report by Song et al showed increased epidermal pigmentation and expression of certain inflammatory cytokines after laser irradiation, suggesting that they may be responsible for induction of PIH [5].…”

Section: Discussionmentioning

confidence: 99%

“…An online MATLAB (MathWorks, Natick, MA, USA) package (LASSOGLM function) was downloaded and applied to fit the LASSO model on a HP Workstation Z640 (Hewlett-Packard, US). The LASSO method was performed with cross-validation (10 times) and the parameters (λ and α values) were set based on the previous studies [3,4,18]. The default settings used for λand α (the elasticnet mixing parameter) were set to 1.…”

Section: Pihcp Evaluation (Lasso)mentioning

confidence: 99%

“…Wanner et al pointed out that immediate endpoints of laser (IEL) is an indicator of laser tissue response and PIH is caused by inflammation [3,4]. Song et al reported that the increase in epidermal pigmentation after laser irradiation is related to the increased expression of certain inflammatory cytokines, suggesting that they may be the cause of PIH induction [5].…”

Section: Introductionmentioning

confidence: 99%

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Evaluating the Risk Factors of Post Inflammatory Hyperpigmentation Complications with Nd-YAG Laser Toning Using LASSO-Based Algorithm

et al. 2020

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The neodymium-doped yttrium aluminum garnet (Nd-YAG) laser is used for removal of pigmented skin patches and rejuvenation of skin. However, complications such as hyperpigmentation, hypopigmentation, and petechiae can occur after frequent treatments. Therefore, identifying the risk factors for such complications is important. The development of a multivariable logistic regression model with least absolute shrinkage and selection operator (LASSO) is needed to provide valid predictions about the incidence of post inflammatory hyperpigmentation complication probability (PIHCP) among patients treated with Nd-YAG laser toning. A total of 125 female patients undergoing laser toning therapy between January 2014 and January 2016 were examined for post-inflammatory hyperpigmentation (PIH) complications. Factor analysis was performed using 15 potential predictive risk factors of PIH determined by a physician. The LASSO algorithm with cross-validation was used to select the optimal number of predictive risk factors from the potential factors for a multivariate logistic regression PIH complication model. The optimal number of predictive risk factors for the model was five: immediate endpoints of laser (IEL), α-hydroxy acid (AHA) peels, Fitzpatrick skin phototype (FSPT), acne, and melasma. The area under the receiver operating characteristic curve (AUC) was 0.79 (95% CI, 0.70–0.88) in the optimal model. The overall performance of the LASSO-based PIHCP model was satisfactory based on the AUC, Omnibus, Nagelkerke R2, and Hosmer–Lemeshow tests. This predictive risk factor model is useful to further optimize laser toning treatment related to PIH. The LASSO-based PIHCP model could be useful for decision-making.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Pihcp Evaluation (Lasso)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Evaluating the Risk Factors of Post Inflammatory Hyperpigmentation Complications with Nd-YAG Laser Toning Using LASSO-Based Algorithm

et al. 2020

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“…It is necessary to perform the laser procedure on absolutely clean and dry skin, to recommend patients to exclude the use of cosmetic products in the intended treatment area 12 hours before the scheduled procedure. The choice of laser radiation parameters taking into account the individual clinical picture, the spectral properties of the target, the size and depth of its occurrence, as well as the characteristics of the patient's skin (skin phototype). Step‐by‐step selection of energy parameters with visual monitoring of tissue changes in the treatment area until the criterion of therapeutic efficiency is reached. When working, it is necessary to focus not so much on the digital values of the parameters as on the clinical changes in tissues in the treatment area under the influence of laser radiation, since the productivity of lasers can vary up to 20% 26 Follow the protocol carefully: control of the correct position of the laser tip, compliance with the scanning mode and the required overlap of spots, an adequate number of passes and maintaining sufficient time intervals between passes. If atypical tissue changes occur in the treatment area, it is necessary to stop immediately and analyze the possible causes of the effect obtained.…”

Section: Etiological Classification Of Laser Complicationsmentioning

confidence: 99%

Management and prevention of laser complications in aesthetic medicine: An analysis of the etiological factors

Kalashnikova¹,

Jafferany

Lotti

2020

Dermatologic Therapy

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Growing popularity of laser treatment has understandably resulted in increased incidence of potential complications. The analysis of complications, taking into account the causes of their occurrence, is of particular interest. The identification of etiological factors and the development of a step‐by‐step prophylactic algorithm with their consideration is the way to reduce the number of possible complications in future practice. In this article, we present a classification of the causes of complications associated with various types of laser procedures. This classification was developed on the basis of a review of last 20 years' literature and our own experience in a network of clinics “Linline” in Russia. We identified six groups of the etiological classification of laser complications: errors of patient selection, errors of treatment tactics, wrong choice of device and technology, neglect of treatment protocol, inadequate post‐procedural care, individual response of the patient. The causes of all specified groups of complication, except the last one, are preventable causes.

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Dynamic Optical Coherence Tomography Imaging of Telangiectasia Prior to Intense Pulsed Light Treatment—An Opportunity to Target Treatment?

et al. 2020

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Background and Objectives To investigate whether optical coherence tomography (OCT) could be utilized to characterize blood flow and vessel dimensions of facial telangiectasias before and during consecutive intense pulsed light (IPL) treatment. Study Design/Materials and methods Dynamic OCT (D‐OCT) was used to image telangiectasia immediately before and after, 1–3 days after, and 1 month after IPL treatment. Measurements included vessel width and depth, blood flow, and attenuation. Vessel dimensions at baseline were verified by a blinded observer. Clinical improvement was detected as good, moderate, or none, and adverse effects were registered at 1‐month follow‐up. Results In total, 14 patients with facial telangiectasia were included. At baseline, vessel width was median 0.25 mm (interquartile range [IQR]: 0.19–0.34 mm) with an intra‐class coefficient (ICC) of 0.89 (95% confidence interval [CI]: 0.70; 0.97). Vessel depth was 0.30 mm (IQR: 0.25–0.33 mm; ICC: 0.40 [CI: −0.07; 0.75]). Vessel depth increased significantly from baseline to 1‐month follow‐up (P = 0.008), whereas no significant changes in vessel width, blood flow, or attenuation were detected. Clinical efficacy seemed related to the relation between vessel dimensions and applied energy settings. Conclusions The D‐OCT imaging technique demonstrated that facial telangiectasias were found deeper within the skin after one IPL treatment. By characterizing the vessel dimensions and blood flow of telangiectasia, D‐OCT may improve efficacy and safety of IPL. Lasers Surg. Med. © 2020 Wiley Periodicals LLC

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Immediate skin responses to laser and light treatments

Cited by 21 publications

References 91 publications

Evaluating the Risk Factors of Post Inflammatory Hyperpigmentation Complications with Nd-YAG Laser Toning Using LASSO-Based Algorithm

Evaluating the Risk Factors of Post Inflammatory Hyperpigmentation Complications with Nd-YAG Laser Toning Using LASSO-Based Algorithm

Management and prevention of laser complications in aesthetic medicine: An analysis of the etiological factors

Dynamic Optical Coherence Tomography Imaging of Telangiectasia Prior to Intense Pulsed Light Treatment—An Opportunity to Target Treatment?

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