Immediate hypersensitivity to Parthenium hysterophorus. II. Clinical studies on the prevalence of parthenium rhinitis

Sriramarao, P.; Nagpal, Sunil; Rao, B. Sanjiva; Prakash, Om; Rao, P. V. Subba

doi:10.1111/j.1365-2222.1991.tb00804.x

Cited by 24 publications

(22 citation statements)

References 15 publications

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“…Jayachandra (1971) stated that the parthenium can be a serious problem in grasslands and can reduce the pasture carrying capacity by up to 90%. It is also known to cause human health problems like asthma, bronchitis, dermatitis, and hay fever (Kololgi et al, 1997;Srirama Rao et al, 1991). Evans (1997) and Towers and Subba Rao (1992) also reported that close contact with P. hysterophorus could cause allergic contact dermatitis while inhalation of pollen can cause allergic rhinitis, which can develop into bronchitis or asthma in susceptible humans.…”

Section: Introductionmentioning

confidence: 99%

Socio-economic impacts of Parthenium hysterophorus L. in East Shewa and West Arsi zones of Ethiopia

Hundessa

Belachew

2017

Int. J. Agril. Res. Innov. & Tech.

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Parthenium hysterophorus L. is non-native invasive plant species belongs to the family Asteraceae. Currently it is a notorious weed in Ethiopia. Socio-economic impacts as well as the local people's perception towards P. hysterophorus are poorly understood. Thus, the aim of this study was to generate information for a better understanding of the means of dispersal, source introduction and socio-economic impacts, of P. hysterophorus in East shewa and West arsi Zones of the Oromia Regional State of Ethiopia. The study revealed that parthenium was introduced mainly by following vehicles road and railways. This weed grows throughout the year. This results in its fast dispersal. Many mechanisms were assumed by respondents for fast distribution of P. hysterophorus in the study zones. Among these vehicles and wind are the major agents, which proliferate the seeds of the weed. Based on the study it grows in roadsides, grazing land, cropland, village sides and wastelands. Most of respondents also indicated that the weed first appeared on roadside and propagated to other habitats. This finding indicated that the weed high in disturbed habitats. Control methods, which are mostly practiced by local people, were tillage and hand weeding. However, these methods were not an efficient to control the weed distribution; rather it is expanding from time to time since its invasions. P. hysterophorus has a number of socioeconomic impacts that include effect on crop and livestock production, human health, soil fertility and biodiversity. This finding showed that it competes and suppress the growth of crops due its allelopathic nature. Seeds of this weed changes the normal flavor of food when mix with it. It also colonized grazing fields, thus causing animal food scarcity, animals' health defect. This finding also reported that P. hysterophorus has health hazards on human being, which include allergic, skin itching (irritation), cough and hemorrhage. Generally, P. hysterophorus is a foremost troublesome weed and subterfuge threat on agriculture, biodiversity and on human health. Therefore, proper and targeted control methods should be employed to control the further spread and reduce the adverse impacts.

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Section: Introductionmentioning

confidence: 99%

Socio-economic impacts of Parthenium hysterophorus L. in East Shewa and West Arsi zones of Ethiopia

Hundessa

Belachew

2017

Int. J. Agril. Res. Innov. & Tech.

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“…The high degree of allergenic crossreactivity, if not identity, established by RAST inhibition and lymphocyte proliferation experiments seems to sug gest that the native proteins of Parthenium and ragweed pollens with different physicochemical properties bear cross-reactive IgE epitopes. The clinical and immunolog ical studies carried out in India established that {he Parthe nium weed, presumed to have been accidentally intro duced into India about 3 decades ago as a contaminant with imported wheat grains, has spread all over the coun try and is responsible for the increasing incidence of al lergic rhinitis (up to 7% of the population in regions heav ily infested with the weed [6]). It is also found to be respon sible for the high incidence of rhinitis in the Brisbane region of Australia where P hysterophorus has spread in recent years [Stewart J.A., personal commun.].…”

Section: Discussionmentioning

confidence: 99%

“…Pollen of P. hysterophorus was collected and processed as de scribed earlier [6], Defatted Parthenium pollen was extracted with PBS (pH 7.4) for 20 h at 4°C (1:10 w/v). The extract was then filtered, centrifuged at 20,000g for 20 min and diluted with equal volumes of glycerol after passing through a sterile Miliporc filter (0.45 urn).…”

Section: Preparation O F Allergen Extracts For Skin Testingmentioning

confidence: 99%

“…It has been shown that Parthenium pollen is responsible for the high incidence of allergic rhinitis in certain parts of India where the weed grows wild [4][5][6], During the past 5 years, it has been noticed that persons from the United States with proven sensitivity to ragweed pollen developed allergic rhinitis when they visited Banga lore (India), where there is luxuriant growth of Parthenium but no ragweed. These patients elicited positive skin prick reaction to both Parthenium and ragweed pollen extracts.…”

Section: Introductionmentioning

confidence: 99%

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Allergenic Cross-Reactivity between Parthenium and Ragweed Pollen Allergens

Sriramarao

Rao

1993

Int Arch Allergy Immunol

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Cross-reactivity of allergens from the pollen of the Compositae weeds, Parthenium hysterophorus (American feverfew) and Ambrosia (ragweed), in 2 groups of patients with different geographic distributions was studied. Parthenium-sensitive Indian patients, who were never exposed to ragweed, elicited positive skin reactions with ragweed pollen extracts. A significant correlation in the RAST scores of Parthenium and ragweed-specific IgE was observed with the sera of Parthenium and ragweed-sensitive Indian and US patients, respectively. RAST inhibition experiments demonstrated that the binding of IgE antibodies in the sera of ragweed-sensitive patients to short (Wl) and giant (W3) ragweed allergen discs could be inhibited by up to 94% by Parthenium pollen extracts. Similar inhibition (up to 82%) was obtained when the sera of Parthenium rhinitis patients were incubated with ragweed allergen extracts. A dose-dependent proliferation of lymphocytes from a Parthenium-sensitive rhinitis patient with elevated levels of both Parthenium and ragweed-specific IgE was observed when incubated with Parthenium and ragweed pollen extracts. A 1.6-fold higher proliferation, however, was observed with Parthenium pollen extract at a concentration of 100 µg/ml. These results suggest that shared epitopes present on Parthenium and ragweed pollen allergens are recognized by both Indian and US patients sensitized by exposure to Parthenium and ragweed pollen, respectively. The high degree of cross-reactivity between Parthenium and ragweed pollen allergens suggests that individuals sensitized to Parthenium may develop type-I hypersensitivity reactions to ragweed and vice versa when they travel to regions infested with the weed to which they had not been previously exposed.

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“…Contact with Parthenium plant parts, in all stages of its life cycle, causes dermatitis in man. Pollens cause air borne contact dermatitis and when inhaled cause allergic rhinitis [27] which can lead to serious respiratory problems such as asthma and bronchitis. The harmful effects are induced by secondary metabolites, particularly parthenin toxin, present in different parts of the plant [28].…”

Section: Detrimental Effectsmentioning

confidence: 99%

Utility Potential ofParthenium hysterophorusfor Its Strategic Management

Saini

Aggarwal

Sharma

et al. 2014

Advances in Agriculture

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Parthenium hysterophorus, one of the world's most dangerous weeds, is responsible for huge losses to the biodiversity, agriculture, economy, and health of livestock and human beings. High competitive success rate and adaptability of the species enable it to dominate diverse types of habitats. Various weed control strategies are being used globally to reduce its population to manageable levels. But owing to many limitations associated with the conventional methods, management of Parthenium still remains a challenge. Recently large scale utilization has been taken up as a holistic approach for the control of weeds. Parthenium hysterophorus can be managed by exploiting this weed in diverse fields. In agriculture, it can be used either as green manure or after composting. Industrially it can be used for producing various value added products. The weed also exhibits many environmental applications. Chemical constituents of Parthenium show extensive range of pharmacological activities suggesting its role as a chemotherapeutic agent. This review briefly discusses the problem of Parthenium and enlists its possible utilities which can open new avenues for effective management of this violent weed.

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Immediate hypersensitivity to Parthenium hysterophorus. II. Clinical studies on the prevalence of parthenium rhinitis

Cited by 24 publications

References 15 publications

Socio-economic impacts of Parthenium hysterophorus L. in East Shewa and West Arsi zones of Ethiopia

Socio-economic impacts of Parthenium hysterophorus L. in East Shewa and West Arsi zones of Ethiopia

Allergenic Cross-Reactivity between <i>Parthenium</i> and Ragweed Pollen Allergens

Utility Potential ofParthenium hysterophorusfor Its Strategic Management

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