Immature Teratoma of the Uterine Fundus.

Iwanaga, Shigeaki; Shimada, Atsuko; Hasuo, Yasuyuki; Yoh, Sansen; Miyajima, Satoshi; Nishimura, Haruo; Yakushiji, M

doi:10.2739/kurumemedj.40.153

Cited by 16 publications

(13 citation statements)

References 11 publications

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“…Teratomas arising from the uterus are extremely rare: Since the first description of a uterine teratoma by Mann in 1929 there have been just a handful of case reports [5]. The majority of these are mature teratomas and there are only three previous reports in the literature of immature teratomas arising from the uterus [6-8]. All previous reports have been in women of reproductive age and to our knowledge this is the first report of a teratoma in a post-menopausal lady.…”

Section: Resultsmentioning

confidence: 99%

Case report: Malignant teratoma of the uterine corpus

et al. 2009

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BackgroundTeratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary. Extragonadal teratomas are rare and mainly occur in midline structures. Uterine teratomas are extremely rare with only a few previous case reports, usually involving mature teratomas of the uterine cervix.Case PresentationWe report an 82-year-old lady presenting with post-menopausal bleeding. Initial investigations revealed a benign teratoma of the uterus which was removed. Her symptoms persisted and a recurrent, now malignant, teratoma of the uterine corpus was resected at hysterectomy. Six months after surgery she relapsed with para-aortic lymphadenopathy and was treated with a taxane, etoposide and cisplatin-containing chemotherapy regimen followed by retroperitoneal lymph node dissection.ConclusionIn this report we discuss the aetiology, diagnosis and management of uterine teratomas, and review previous case studies.

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Section: Resultsmentioning

confidence: 99%

Case report: Malignant teratoma of the uterine corpus

et al. 2009

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“…Therefore, most of the evidence for stage I disease after surgical treatment is obtained from case reports. In these case reports, clinical observations were used to determine various treatment methods, and these included two cycles of chemotherapy vincristine, actinomycin-D, and cyclophosphamide (VAC), 2,4 an undescribed treatment regimen, 3 and radiotherapy (Table 1). 2-5 In addition, not all of the reports described patient follow-up and outcomes, thereby preventing a comparison of treatment decisions.…”

Section: Discussionmentioning

confidence: 99%

“… 2-5 In addition, not all of the reports described patient follow-up and outcomes, thereby preventing a comparison of treatment decisions. Iwanaga et al 4 reported a patient that received adjuvant treatment with VAC, and subsequently presented no evidence of tumor recurrence five years post-treatment.…”

Section: Discussionmentioning

confidence: 99%

Immature Uterine Teratoma Associated with Uterine Inversion

et al. 2014

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Teratomas are the most commonly diagnosed germ cell tumors and occur primarily in testes and ovaries. Platinum-based therapy followed by surgical resection of the residual lesion is generally the recommended treatment. In contrast, immature uterine teratomas are rare, with few cases reported in the literature. Moreover, there is no standard treatment for these tumors. Non-puerperal uterine inversion is also rare in women younger than 45 years of age, and neoplastic lesions are responsible for this condition. Here, we report a case of an immature uterine teratoma associated with uterine inversion. The patient underwent surgery followed by adjuvant chemotherapy and continues to be monitored.

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“…As the benefit of adjuvant chemotherapy is not clearly established, surveillance can be a reasonable option [12]. Iwanaga et al reported a case of 36-year-old woman, treated by surgery followed by two courses of VAC chemotherapy regimen without evidence of recurrence five years postoperatively [7]. In the paper published by Ansah-Boateng et al, the patient was treated by hysterectomy followed by pelvic radiotherapy; she has remained well with no evidence of recurrence [8].…”

Section: Discussionmentioning

confidence: 99%

Primary Immature Teratoma of the Uterus Relapsing as Malignant Neuroepithelioma: Case Report and Review of the Literature

Mohtaram

Kharmoum

Aaribi

et al. 2013

Case Reports in Oncological Medicine

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Background. Although some mature cases of teratomas have recently been described in the cervix, they are not commonly found in the uterus, especially in immature forms. An immature uterine teratoma relapsing after surgery as malignant neuroepithelioma has never been reported in the literature. Case Presentation. We describe a case of immature teratoma which occurred primarily in the uterus in a 56-year-old female. Treatment consisted of total simple hysterectomy. Three months after surgery, the patient relapsed with voluminous pelvic mass and was treated with bleomycin, etoposide, and cisplatin-containing chemotherapy regimen. Conclusion. In this report and according to the pertinent literature, clinical and pathological features and management of uterine immature teratomas are discussed. The mainstay of treatment is surgery. The prognosis of this unusual disease remains uncertain.

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Immature Teratoma of the Uterine Fundus.

Cited by 16 publications

References 11 publications

Case report: Malignant teratoma of the uterine corpus

Case report: Malignant teratoma of the uterine corpus

Immature Uterine Teratoma Associated with Uterine Inversion

Primary Immature Teratoma of the Uterus Relapsing as Malignant Neuroepithelioma: Case Report and Review of the Literature

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