Imaging Techniques Used in the Diagnosis of Pediatric Tumors

McCarville, M. Beth

doi:10.1007/978-1-4939-1729-7_2

Cited by 5 publications

(1 citation statement)

References 51 publications

(35 reference statements)

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“…18 F-fluorodeoxyglucose positron emission tomography/CT should become a part of the standard diagnostic algorithm for children diagnosed with RMS, although dedicated bone imaging with 99 Tc-methylene diphosphonate bone imaging may not be necessary in these patients. To reduce the radiation exposure of pediatric RMS patients to a minimum, as demanded by the As Low As Reasonably Achievable principle (38,39), the number of imaging procedures should be as low as possible, since children are 10-15 times more sensitive to radiation than adults (40). Furthermore, children with RMS are often under surveillance for numerous years with serial CT imaging; thus, the development of novel imaging approaches to reduce radiation exposure is required (41).…”

Section: Discussionmentioning

confidence: 99%

Management of pediatric head and neck rhabdomyosarcoma: A case-series of 36 patients

Radzikowska

Kukwa

et al. 2016

Oncology Letters

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Abstract. Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in the pediatric population. In 35% of cases, RMS develops in the head and neck (H&N) region, and only combined therapy is recognized as a curative treatment. However, recent advances in skull base and reconstructive surgery, along with microsurgery and endoscopic surgery, have strengthened the role of surgery as an important part of RMS treatment. In the present study, 36 pediatric RMS cases (24 males and 12 females) were analyzed after surgical treatment. The average age at diagnosis was 7 years. In total, 67% of tumors were localized in the parameningeal region. Alveolar RMS was the most common histopathological type. A total of 16 patients were treated due to disease recurrence or a previous non-radical surgical procedure, while 19 cases had inductive chemotherapy and/or radiotherapy preceding surgical treatment due to locally advanced disease. In 1 case, only diagnostic biopsy was performed. It is recommended that the management of H&N RMS is interdisciplinary from the beginning. Extensive surgical dissection in the H&N region for RMS may result in severe cosmetic defects and functional impairment; thus, these risks should be considered during treatment planning, and the surgical approach should be based on the individual characteristics of each patient.

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