Imaging Studies in Partial Epilepsy in Children and Adolescents

Abstract

We reviewed the results of imaging studies on 111 children and adolescents with partial epilepsy to determine which imaging procedure had the greatest sensitivity and specificity for partial epilepsy in this age range. All cases were classified as idiopathic, lesional, and cryptogenic epilepsy based on the 1989 International League Against Epilepsy Classification. All patients had magnetic resonance imaging (MRI) and 98 also had computed tomography (CT). Thirty patients with negative CT had MRI lesions that were most likely the cause of the epilepsy, and the initial diagnosis of cryptogenic partial epilepsy was changed to lesional partial epilepsy. We concluded that CT use is unwarrantedly common. MRI should be considered the procedure of first choice. CT has a complementary role, and functional neuroimaging should be encouraged.

Imaging in Pediatric Epilepsy: Spectrum of Abnormalities Detected on Mri

“…Resta et al [11] reported positive MRI in 51.3%, Wang et al [12] in 41.7% and Chang et al [8] in 48.9%. Our study shows a higher percentage, probably because of strict exclusion criteria's, which shows that patient selection, plays an important role in MR positivity rates.…”

3.0 T MRI of 2000 consecutive patients with localisation-related epilepsy

“…In paediatric studies, the rate of seizure-related abnormalities ranges between 13% and 51% [5][6][7][8][9][10]. In adults the rates are similar (13-55%), but the number of patients studied is relatively low and the selection criteria for MRI vary substantially [11][12][13].…”

Evaluation of Non Febrile Seizure Disorder on Mri with Correlation with Seizure Type And EEG Records in Children.

“…Two most common abnormalities detected on MRI were granulomatous lesion in 56(33.3%) cases and hypoxic ischemic encephalopathy in 12 (7.1%) cases.Likewise CNS infections/infestations, previous insult, and perinatal insult have been found to be most common etiologies associated with seizures in studies done by (24) and Resta et al (25) have also found higher frequency of abnormal neuroimaging with partial seizures.In our study according the seizure type EEG abnormality was highest (67%) in case of partial seizures while it was lowest in case of generalised seizures (44.6%).This is in partial agreement with study by Rasool et al (23) who found high rate of EEG abnormality in case of both partial and generalised seizures (approx.70%).There was moderate positive correlation between abnormality detection on EEG and MRI. (Pearson correlation coefficient r=0.65).…”