Introduction: CNS infections are an emerging health problem with poor prognosis if the treatment is not prompt and adequate. Thus, establishing a correct diagnosis is necessary to quickly start the appropriate treatment. This study was undertaken to study the etiology and the imaging spectrum of CNSI in and around western Uttar Pradesh in a tertiary health care set up and to correlate the neuro-imaging findings with clinic-pathological data. Material and Methods:In this Prospective Observational study 80 patients clinically suspected of CNS infection were studied by CT/MRI and the neuro imaging findings were correlated with clinical and CSF findings.Results: Based on clinical features, CSF findings, the treatment given and the response to treatment tuberculous infection (TBM) was most common infection (41.2%) followed by pyogenic meningitis (36.2%) and viral infection (22.5%). In 29 patients of pyogenic CNS infection most common imaging finding was leptomeningitis(62%) followed by pachymeningitis (31%), hydrocephalus (24.1%), abscess (6.8%), post vasculitic infarct(6.8%) and extra axial collection(6.8%). In 33 patients of tubercular CNS infection most common imaging finding was basal leptomeningitis (78.7%) followed by tuberculoma (72.7%), pachymeningitis (33.3%), hydrocephalus (27.2%), abscess (12.1%), post vasculitis infarct (12.1%) and spinal cord involvement in 1 (3%) patient. In the 18 viral CNS infection cases most common imaging finding was parenchymal hyperintensity on MRI or hypodensity on CT with/without peripheral vasogenic edema (94.4%) followed by leptomeningeal/pachymeningeal involvement (61.1%) and post vasculitis infarct (11.1%). Conclusion:The sensitivity of neuroimaging in pyogenic CNS infection was 81.2% and specificity was 93.7% while sensitivity of neuroimaging in tubercular CNS infection was 88.8% and specificity was 97.8% and in viral CNS infection sensitivity was 84.2% and specificity was 96.7%. There was significant association (p value <0.05) of basal leptomeningitis and granulomas on imaging with tubercular infection and parenchymal signal changes with viral infections.
Background: Pulmonary infections are among the most common infections encountered in outpatient and inpatient clinical care. The most useful imaging modalities available for the evaluation of the patient with suspected pulmonary infection are chest radiography and computed tomography (CT).The aim of present study is to evaluate various patterns of pulmonary disease depicted radio logically and to establish and compare sensitivity and specificity of radiography and computed tomography. 64.66 % and 75% respectively with PPV and NPV of 98.68% and 6.82% respectively. CT scan showed Sensitivity, Specificity, PPV and NPV of 87.10%, 98.89 %, 96.43% and 95.70% respectively for the diagnosis of pyogenic bacterial infections, Sensitivity, Specificity, PPV and NPV of 95.70 %, 97.87 %, 98.63% and 95.83 % respectively for the diagnosis of mycobacterial infections and Sensitivity, Specificity, PPV and NPV of 93.33%, 99.06 %, 93.33% and 99.06 Materials and Methods: This prospective observational study included a total of 120 patients with suspected pulmonary infections referred for chest imaging. Chest radiography examination was done in all the patients. Subsequently all of the patients underwent either contrast enhanced and/or non contrast high resolution computed tomography of the chest as appropriate on 128 slice Philips Multi-detector CT (MDCT). Imaging finds were interpreted independently and tabulated and subsequently correlated with clinical and pathological findings. Results: Most of the patients were in the 51 to 60 years age group (29.2%) with male predominance (55%). Sensitivity and specificity of chest X-ray in detection of pulmonary infections was
<p class="abstract"><strong>Background:</strong> The impact of acute and sub lethal toxicity of synthetic Rogor on some biochemical and hematological parameters of a fish <em>Amphipnous cuchia</em> was estimated aquatic environment by various pollutants like pesticides, detergents, discharge of effluents and heavy metals induce changes in the biochemical, hematological and behavioral aspects of inhabitants. These pollutants cause serious effects on growth, biochemistry, physiology, neurochemistry and survival rate of the aquatic organism<span lang="EN-IN">. </span></p><p class="abstract"><strong>Methods:</strong> The present research work is one such attempt to investigate the effect of organophosphorous pesticide Rogor on biochemical and hematological parameters of fish <em>Amphipnous cuchia</em>. The main objective of this study was to investigate the level of AST, ALT, hematocrit and TLC in fish <em>Amphipnous cuchia</em> exposed 24 to 96 hours to four different concentrations of Rogor pesticide<span lang="EN-IN">.</span></p><p class="abstract"><strong>Results:</strong> Rogor toxicity resulted in a significant maximum increase (89.15%) in level of aspartate amino transferase (7.87±0.14<strong>/</strong>18.31±0.09) and alanine amino transferase (76.65%, 5.28±0.11<strong>/</strong>3.03±0.14) enzyme. Regarding to hematological parameter, significant maximum increase (77.12%) in total leukocyte count (27,400±298<strong>/</strong>15,470±286) and maximum decrease (66.07%) in hematocrit (6.20±0.04 <strong>/</strong>18.31±0.09) level was observed<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> In this study<strong> </strong>it is concluded that exposure to sublethal/lethal concentration of Rogor results in a significant alterations in different biochemical and hematological parameters and this kind of biochemical and physiological changes may directly affect the survivability of these fishes in these natural habitat.</p>
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