Imaging of hepatic transplantation

Hussain, Hero K.; Nghiem, Hanh V.

doi:10.1016/s1089-3261(03)00075-8

Cited by 21 publications

(2 citation statements)

References 93 publications

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“…Orthotopic liver transplantation (OLT) is actually considered the best treatment option for end-stage liver disease, as well as for acute hepatic failure [1] . Despite the continuous improvement in survival over the years [2] , biliary complications are still common and represent important causes of mortality (between 2% and 7%), morbidity, and graft dysfunction after OLT. Adverse events such as biliary strictures, stones and leakages, can occur in a percentage ranging between 5.8% and 24.5% of adult liver transplant recipients and their prompt identification and appropriate management is essential for the survival of graft and patient [3] , [4] .…”

Section: Introductionmentioning

confidence: 99%

Biliary complications following orthotopic liver transplantation: May contrast-enhanced MR Cholangiography provide additional information?

Boraschi¹,

Donati²,

Gigoni³

et al. 2016

European Journal of Radiology Open

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PurposeTo assess whether contrast-enhanced T1-weighted MR Cholangiography may provide additional information in the evaluation of biliary complications in orthotopic liver transplant recipients.Material and methodsEighty liver transplant patients with suspicion of biliary adverse events underwent MR imaging at 1.5 T scanner. After acquisition of axial T1-/T2-weighted images and conventional T2-weighted MR Cholangiography (image set 1), 3D gradient-echo T1-weighted fat-suppressed LAVA (Liver Acquisition with Volume Acceleration) sequences were obtained about 30 min after intravenous infusion of mangafodipir trisodium (Mn-DPDP,Teslascan®) (image set 2). The diagnostic value of mangafodipir trisodium-enhanced MR Cholangiography in the detection of biliary complications was tested by separate analysis results of image set 1 alone and image set 1 and 2 together. MRI results were correlated with direct cholangiography in 46 patients, surgery in 14 and/or clinical-radiological follow-up in the remaining 20 cases.ResultsThe level of confidence in the assessment of biliary adverse events was significantly increased by the administration of mangafodipir trisodium (p < 0.05). Particularly, contrast-enhanced T1-weighted LAVA sequences tended to out-perform conventional T2-weighted MR Cholangiography in the delineation of anastomotic and non-anastomotic biliary strictures and in the diagnosis of biliary leak.ConclusionsContrast-enhanced T1-weighted MR Cholangiography may improve the level of diagnostic confidence provided by conventional T2-weighted MR Cholangiography in the evaluation of biliary complications after orthotopic liver transplantation.

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Section: Introductionmentioning

confidence: 99%

Biliary complications following orthotopic liver transplantation: May contrast-enhanced MR Cholangiography provide additional information?

Boraschi¹,

Donati²,

Gigoni³

et al. 2016

European Journal of Radiology Open

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“…[1] Although initial efforts were unsuccessful, after several years of improvements in surgical techniques and the introduction of new immunosuppressive agents, liver transplantation currently has a 5-year survival rate of approximately 75%. [2][3][4] Deceased donor liver transplantation (DDLT) is the typical surgical technique adopted; however, due to a lack of appropriately sized donors and the high mortality rate among children on the waiting list, split liver transplantation and, subsequently, living donor liver transplantation (LDLT) have been introduced since the late 1980s. Manuscript 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 …”

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confidence: 99%

Imaging follow-up after liver transplantation

Martino¹,

Rossi²,

Mennini³

et al. 2016

BJR

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Liver transplantation (LT) represents the best treatment for end-stage chronic liver disease, acute liver failure and early stages of hepatocellular carcinoma. Radiologists should be aware of surgical techniques to distinguish a normal appearance from pathological findings. Imaging modalities, such as ultrasound, CT and MR, provide for rapid and reliable detection of vascular and biliary complications after LT. The role of imaging in the evaluation of rejection and primary graft dysfunction is less defined. This article illustrates the main surgical anastomoses during LT, the normal appearance and complications of the liver parenchyma and vascular and biliary structures.

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Bile acids for liver-transplanted patients

Chen

Gluud

2005

Cochrane Database of Systematic Reviews

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Imaging of hepatic transplantation

Cited by 21 publications

References 93 publications

Biliary complications following orthotopic liver transplantation: May contrast-enhanced MR Cholangiography provide additional information?

Biliary complications following orthotopic liver transplantation: May contrast-enhanced MR Cholangiography provide additional information?

Imaging follow-up after liver transplantation

Bile acids for liver-transplanted patients

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