Imaging of Heart Disease in Women

Tailor, Tina D.; Kicska, Gregory; Jacobs, Jill E.; Pampaloni, Miguel Hernandez; Litmanovich, Diana; Reddy, Gautham P.

doi:10.1148/radiol.2016151643

Cited by 8 publications

(2 citation statements)

References 143 publications

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“…Cardiovascular disease during pregnancy includes aggravation of preexisting conditions such as congenital heart disease, hemodynamic maladaptation, and peripartum cardiomyopathy (PPCM) [48]. Preeclampsia, eclampsia, and HELLP syndrome are manifestations of vascular dysfunction during pregnancy and are characterized by hypertension, end-organ injury, edema, and neurological symptoms.…”

Section: Pregnancy-related Heart Diseasementioning

confidence: 99%

Cardiovascular Disease in Women: What the Radiologist Needs to Know

Sommer¹,

Hergan

2022

Rofo

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Background Sex-specific disparities are well documented for cardiovascular disease (CVD). There are differences in physiology and pathophysiology, pain perception, spectrum of disease, risk, therapeutic aspects, prognosis, and outcome. CVD represents a broad spectrum of disorders. This review focuses on cardiovascular and cardiac pathology. Method This review summarizes the current state of the literature on cardiovascular disease in women from a radiological viewpoint. It aims to provide a deeper understanding of these differences and thereby alerts the reader to the potential of CT and MRI for diagnosing CVD in women. Special attention is paid to disparities in the underlying physiological and pathophysiological processes, clinical presentation, and the quality of care to provide a deep understanding of the topic. Cardiovascular and cardiac pathologies with a sex-specific pattern of disease are presented and typical CT and MRI findings are arranged and illustrated with imaging findings. Results and Conclusion Sex-specific differences are not only sex hormonal in nature but are rooted in the epigenome and encompass a multitude of physiological systems. In fact, cardiovascular disease shows sex-specific characteristics spanning from incidence to clinical presentation, course of disease, and prognosis. This is of significance regarding pretest probabilities, the power of tests, imaging strategies, and interpretation of imaging results. Key sex-specific issues encompass obstructive and non-obstructive coronary artery disease (CAD), microvascular angina, myocardial infarction with non-obstructive CAD, and coronary artery dissection. Sex-specific patterns are also noted in myocardial disease and heart failure such as pregnancy-related heart disease, Takotsubo syndrome, and anthracycline-induced cardiotoxicity. Key points:

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Section: Pregnancy-related Heart Diseasementioning

confidence: 99%

Cardiovascular Disease in Women: What the Radiologist Needs to Know

Sommer¹,

Hergan

2022

Rofo

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“…There are anatomic differences between men and women that are related to pitfalls alterations in diagnostic performance of cardiac imaging modalities. Furthermore, clinical presentation of symptoms may differ between genders, making women more vulnerable for delayed diagnosis and therapeutic approach [ 27 ]. Women should undergo careful investigation, as clinical symptoms might be atypical.…”

Section: Non-traditional Risk Factors For Cvd In Womenmentioning

confidence: 99%

Cardiovascular disease in women: Executive summary of the expert panel statement of women in cardiology of the hellenic cardiological society

Chrysοhoou

Aggeli

Avgeropoulou

et al. 2020

Hellenic Journal of Cardiology

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The perception that women represent a low risk population for cardiovascular (CV) disease (CVD) needs to be reconsidered. Starting from risk factors, women are more likely to be susceptible to unhealthy behaviors and risk factors that have different impact on CV morbidity and mortality compared to men. Despite the large body of evidence as regards the effect of lifestyle factors on the CVD onset, the gender-specific effect of traditional and non-traditional risk factors on the prognosis of patients with already established CVD has not been well investigated and understood. Furthermore, CVD in women is often misdiagnosed, underestimated and undertreated. Women also experience hormonal changes from adolescence till elder life that affect CV physiology. Unfortunately, in most of the clinical trials women are under-represented, leading to limited knowledge of CV and systemic impact effects of several treatment modalities on women’s health. Thus, in this consensus a group of female Cardiologists from the Hellenic Society of Cardiology present the special features of CVD in women: the different needs in primary and secondary prevention, as well as therapeutic strategies, that may be implemented in daily clinical practice in order to eliminate underestimation and undertreatment of CVD in female population.

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