Imaging Diagnosis—computed Tomographic, Surgical, and Histopathologic Characteristics of an Infiltrative Angiolipoma in a Dog

Kraun, Michael B.; Nelson, Nathan C.; Hollinger, Charlotte

doi:10.1111/vru.12178

Cited by 6 publications

(13 citation statements)

References 19 publications

(53 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Both modalities have been proven to be useful in identifying and characterizing adipose masses . In veterinary medicine there are a few reports describing adipose tumors, but there is only limited information available on their CT features . Moreover, a comparison between benign and malignant fatty masses based on CT characteristics in a larger group of animals has not been reported.…”

Section: Introductionsupporting

confidence: 83%

Comparisons Among Computed Tomographic Features of Adipose Masses in Dogs and Cats

Spoldi

Schwarz

Sabattini

et al. 2016

Vet Radiology Ultrasound

View full text Add to dashboard Cite

A better understanding of the CT features of different forms of canine and feline adipose tumors would be valuable for improving patient management and treatment. The purpose of this retrospective, cross-sectional study was to describe and compare the CT features of pathologically confirmed lipomas, infiltrative lipomas, and liposarcomas in a sample of canine and feline patients. A total of 50 animals (46 dogs, four cats) and a total of 60 lesions (23 lipomas, 20 infiltrative lipomas, and 17 liposarcomas) were included in the study. Lipomas appeared as round to oval-shaped (n = 21), well-marginated (n = 20) fat-attenuating lesions. Infiltrative lipomas appeared as homogeneous, fat-attenuating masses but, unlike lipomas, they were most commonly characterized by an irregular shape (75%; P < 0.001), and linear components, hyperattenuating relative to the surrounding fat (100%; P < 0.05). Liposarcomas were represented exclusively by heterogeneous lesions with soft tissue attenuating components with a multinodular appearance (76.5%; P < 0.05). Regional lymphadenopathy (n = 10) and amorphous mineralization (n = 4) were also observed in association with liposarcomas. Computed tomography can provide useful information regarding disease location, extent, and involvement of the adjacent structures. Tumor definition and shape were the most useful parameters to differentiate between lipomas and infiltrative lipomas. The presence of a heterogeneous mass, with a multinodular soft tissue component and associated regional lymphadenopathy and mineralization, were features favoring a diagnosis of liposarcoma.

show abstract

Section: Introductionsupporting

confidence: 83%

Comparisons Among Computed Tomographic Features of Adipose Masses in Dogs and Cats

Spoldi

Schwarz

Sabattini

et al. 2016

Vet Radiology Ultrasound

View full text Add to dashboard Cite

show abstract

“…, Kraun et al . ). MRI is potentially superior to CT because of its ability to distinguish difference in soft tissues, but direct clinical comparisons have not been performed in the dog (LeBlanc & Daniel ).…”

Section: Treatment Planningmentioning

confidence: 97%

“…This allows the clinician to determine pre-operatively whether the STS is anatomically confined to well-delineated tissue barriers, or has spread beyond such compartments into ill-defined fascial planes and spaces (Hahn et al . 1990, Kraun et al . 2015.…”

Section: Planningmentioning

confidence: 99%

Soft tissue sarcoma in the dog – part 1: a current review

Bray

2016

J of Small Animal Practice

102

View full text Add to dashboard Cite

Soft tissue sarcomas are derived from tissues of mesenchymal origin. Although local recurrence following surgical resection is the characteristic challenge in their management, 40% dogs with high‐grade tumours may also develop metastatic disease, despite successful local control. Soft tissue sarcoma is a complex disease and there are many uncertainties regarding the biology and optimal clinical management. There are currently no diagnostic tests that can reliably predict the amount of surgical margin required for a particular tumour, so there can be a mismatch between treatment and disease. Historically, the tendency has been to always recommend wide excision margins but this is not fully supported by recent evidence. A selection bias for less aggressive soft tissue sarcomas in primary care practice can account for good outcomes that are achieved despite narrow surgical excision margins. On the other hand, inappropriately conservative treatment will adversely affect outcomes for patients with more aggressive disease. This review provides an update on the current understanding of management of canine soft tissue sarcomas.

show abstract

“…Infiltrative lipomas also arise from adipocytes in the subcutaneous tissue and are considered benign because they do not metastasise. However, they infiltrate into adjacent tissues such as muscle, fascia and occasionally bone (Bergman and others 1994, Pereira and others 2005, Morgan and others 2007, Kraun and others 2015). Patients usually are often asymptomatic but may show clinical signs related to compression of adjacent tissues.…”

Section: Discussionmentioning

confidence: 99%

Mandibular infiltrative lipoma in a mixed breed dog

Lai

Selmic²,

Hummel³

et al. 2017

Vet Record Case Reports

View full text Add to dashboard Cite

Lipoma is a neoplastic process of well-differentiated adipocytes that is clearly demarcated from the adjacent tissues. An infiltrative lipoma has histopathological features similar to a simple lipoma, with well-differentiated adipose cells. The distinctive difference with infiltrative lipoma is the capacity to infiltrate into surrounding tissues such as muscle fibres, vessels, nerves and bones. Considering the cytologically benign characteristics of this tumour, the diagnosis of infiltrative lipoma must be confirmed by histological assessment to identify margin and involvement of surrounding tissue. This case report provides an additional differential diagnosis (infiltrative lipoma) to consider when seeing a canine patient with facial mass. In the case described here, wide resection of the mandibular infiltrative lipoma provided long-term remission without the need of additional treatment.

show abstract

Imaging Diagnosis—computed Tomographic, Surgical, and Histopathologic Characteristics of an Infiltrative Angiolipoma in a Dog

Cited by 6 publications

References 19 publications

Comparisons Among Computed Tomographic Features of Adipose Masses in Dogs and Cats

Comparisons Among Computed Tomographic Features of Adipose Masses in Dogs and Cats

Soft tissue sarcoma in the dog – part 1: a current review

Mandibular infiltrative lipoma in a mixed breed dog

Contact Info

Product

Resources

About