A better understanding of the CT features of different forms of canine and feline adipose tumors would be valuable for improving patient management and treatment. The purpose of this retrospective, cross-sectional study was to describe and compare the CT features of pathologically confirmed lipomas, infiltrative lipomas, and liposarcomas in a sample of canine and feline patients. A total of 50 animals (46 dogs, four cats) and a total of 60 lesions (23 lipomas, 20 infiltrative lipomas, and 17 liposarcomas) were included in the study. Lipomas appeared as round to oval-shaped (n = 21), well-marginated (n = 20) fat-attenuating lesions. Infiltrative lipomas appeared as homogeneous, fat-attenuating masses but, unlike lipomas, they were most commonly characterized by an irregular shape (75%; P < 0.001), and linear components, hyperattenuating relative to the surrounding fat (100%; P < 0.05). Liposarcomas were represented exclusively by heterogeneous lesions with soft tissue attenuating components with a multinodular appearance (76.5%; P < 0.05). Regional lymphadenopathy (n = 10) and amorphous mineralization (n = 4) were also observed in association with liposarcomas. Computed tomography can provide useful information regarding disease location, extent, and involvement of the adjacent structures. Tumor definition and shape were the most useful parameters to differentiate between lipomas and infiltrative lipomas. The presence of a heterogeneous mass, with a multinodular soft tissue component and associated regional lymphadenopathy and mineralization, were features favoring a diagnosis of liposarcoma.
Excellent outcomes have been reported following thyroidectomy for thyroid carcinoma in dogs, but outcomes for thyroid carcinomas with gross vascular invasion are poorly described. This study describes the clinical outcomes and complications in dogs with thyroid carcinomas with gross vascular invasion undergoing thyroidectomy. Medical records of dogs that underwent thyroidectomy between January 1st 2010 and December 31st 2019 were reviewed at 10 hospitals. Signalment, diagnostic data, primary and adjuvant treatments performed, and outcome were abstracted. Survival was calculated using Kaplan–Meier analysis. Multiple logistic regression was used to identify variables associated with disease‐specific survival. Seventy‐three dogs were included, of which 58 underwent unilateral thyroidectomy and 15 underwent bilateral thyroidectomy. Complications were reported in five dogs (three major, two minor; 6.8%) intraoperatively and 12 dogs (two major leading to death, 10 minor; 16.4%) postoperatively. Seven (9.6%) dogs developed locoregional recurrence at a median of 238 days postoperatively (range: 15–730 days). Distant metastasis was suspected or confirmed in nine dogs (12.3%) at a median of 375 days postoperatively (range: 50–890 days). Twenty‐seven dogs (37%) received adjuvant therapy (chemotherapy: n = 21; radiotherapy: n = 6). Thirty‐nine dogs were euthanized or died, with 20 deaths related to disease (n = 10) or of unknown cause (n = 10), 19 due to unrelated causes, and nine lost to follow‐up. Median overall and disease‐specific survival were 621 days and not reached respectively. One‐year disease‐specific survival rate was 82.5%. No variables were associated with disease‐specific survival in our dataset. Surgery may be considered for loco‐regional therapy in dogs with thyroid carcinoma with gross vascular invasion.
An 11-year-old, female spayed, domestic shorthair cat with a 1-week history of vomiting was diagnosed with a gastrogastric intussusception using ultrasound. Distinguishing ultrasonographic findings included invagination of the gastric fundus into the body and were correlated to radiographs acquired at the time of the evaluation. Spontaneous resolution of the gastrogastric intussusception was observed on a positive-contrast upper gastrointestinal fluoroscopic study done the following day.Due to worsening comorbidities, which most significantly included chronic renal disease and pancreatitis, and declining quality of life, the patient was humanely euthanized 10 months later. Necropsy revealed no gross and histopathologic abnormalities associated with the stomach. A definitive cause for the intussusception remains unknown.
A 13-year-old, male neutered domestic short-haired cat was diagnosed with multiple biliary duct hamartomas after liver lobectomy for a suspected malignant hepatic mass. Distinguishing ultrasonographic findings included a lobular, mostly well-defined, heterogeneous, predominantly hyperechoic, left hepatic mass. Computed tomography (CT) confirmed the presence of a lobular, well-defined, fluid to soft tissue attenuating, heterogeneously hypoenhancing left divisional hepatic mass. Grossly, a large left sided multilobular pale pink gelatinous hepatic mass was surgically excised. Histopathologically, the mass was composed of irregular cystic spaces lined by cuboidal epithelium and separated by mature regular fibrous tissue. Three months following surgery there was no evidence of recurrence or progression of disease on repeat abdominal ultrasound (AUS).
The variability in diagnostic imaging caseload, increasing class sizes, high hospital workloads, and the progressive departure of veterinary radiologists from academia can lead to inconsistent and reduced teaching opportunities. This one group pretest, posttest study aimed to compare the learning outcomes of students enrolled in two veterinary radiology clerkship models. Our hypothesis was that the learning and satisfaction scores of students in a case‐based veterinary radiology clerkship would be higher than those in a clinical veterinary radiology clerkship. During the spring and summer semesters of 2019, students were assigned to a clinical (CRC) or case‐based (CBRC) radiology clerkship model, respectively. Prior to starting the clerkship and at the conclusion thereof, all students took identical radiographic interpretation quizzes. Four major areas of learning were assessed: knowledge base (KB), diagnostic test interpretation (DTI), problem prioritization and differential diagnosis (PPDDX), and critical thinking (CrT). A total of 41 of 48 (CRC) and 130 of 151 (CBRC) students enrolled in this study; 15 and 34, respectively, were off‐shore students, while the remainder were in‐house students. In‐house students improved their scores with CRC and CBRC, but achieved better scores in the four areas with CBRC. Off‐shore students only improved their scores with CBRC. In both groups, there was a negative effect of CRC on DTI. Course satisfaction score was 3.21 on CRC and 4.38 on CBRC (range 1‐5). An intensive, case‐based, discussion‐focused veterinary radiology clerkship can improve students’ radiographic interpretation skills and overall course satisfaction scores.
| CASE PRESENTATIONAn 11-year-old, neutered male, Labradoodle was presented to the University of Florida's Small Animal Hospital for restaging of a meibomian gland carcinoma removed from his right inferior eyelid 3 years prior. On presentation, the dog had multiple masses throughout the body, including several subcutaneous lipomas and a cutaneous keratin-filled lesion between the ears, which were diagnosed by fine-needle aspiration and cytologic evaluation. A CBC and chemistry profile revealed a mild normocytic normochromic anemia (packed cell volume [PCV] 37%, reference interval [RI] 40-56; mean corpuscular volume [MCV] 69.2 fL, RI 64.0-74.0; mean corpuscular hemoglobin concentration (MCHC) 34.3, RI 33.0-38.0) and a moderately increased ALT activity (303 U/L, RI 18.0-64.0). A triple-phase helical computed tomography (CT) of the thorax, abdomen, and pelvis was performed for metastasis screening. A welldefined, heterogeneous, fat-and fluid-attenuating, bilobed mass was found within the left ventral peritoneal space, between the greater curvature of the stomach and the spleen, and ventral to the transverse colon. The mass measured approximately 12.0 × 6.5 × 6.5 cm (L × H × W) and was characterized by a soft tissue, contrast-enhancing capsule, a large, fluid-filled, non-contrast enhancing, irregularly margined central component, and multiple linear hyperattenuating striations within the fat-attenuating, non-contrast enhancing periphery (Figure 1). Multiple, hyperattenuating striations were seen within the peritoneal fat surrounding the mass. A fine-needle aspirate was submitted for cytologic evaluation (Figure 2).
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