Imaging Characteristics of Recurrent Pleomorphic Adenoma of the Parotid Gland

Moonis, Gul; Patel, Priyesh N.; Koshkareva, Yekaterina; Newman, Jason G.; Loevner, Laurie A.

doi:10.3174/ajnr.a0598

Cited by 43 publications

(20 citation statements)

References 32 publications

(52 reference statements)

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“…The tumours that we analyzed had the same pattern as previously described: epithelial and myoepithelial cells without atypia and pleomorphic architecture . The incidence of tumour recurrence was 7.9%, whereas other groups have reported PA to have a recurrence rate of 20–45% …”

Section: Discussionmentioning

confidence: 78%

“…21,23 The incidence of tumour recurrence was 7.9%, whereas other groups have reported PA to have a recurrence rate of 20-45%. 22,24 In our samples, CD24 and CD44 were expressed throughout the progression of salivary glands from morphogenesis to neoplastic lesion (with pleomorphic adenoma as a model). CD24 and CD44 are used as stem cell markers in various tissues and organs, detected by various techniques.…”

Section: Discussionmentioning

confidence: 89%

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CD24 and CD44 in salivary gland pleomorphic adenoma and in human salivary gland morphogenesis: differential markers of glandular structure or stem cell indicators?

et al. 2013

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Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 89%

CD24 and CD44 in salivary gland pleomorphic adenoma and in human salivary gland morphogenesis: differential markers of glandular structure or stem cell indicators?

et al. 2013

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“…MRI not only has excellent spatial resolution, but it can also determine involvement of the facial nerve, perineural areas, bone, and meninges. Furthermore, MRI confers excellent visibility of the neoplasm on T2 weighted images [16] .…”

Section: Discussionmentioning

confidence: 99%

A unique case of benign pleomorphic adenoma metastasizing to the thyroid gland and liver

Moonim

Wiles

Nasir

et al. 2015

CRCP

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AbstractsA recurrent benign metastasizing pleomorphic salivary adenoma (PSA) is extremely rare occurring in less than 1% of patients. There are approximately 50 cases that have been reported in the literature but none with metastases to the thyroid gland. We report a case of a 68-year-old lady who was initially investigated for a space-occupying lesion in the liver but was found to have metastases in the thyroid and liver as well as recurrence of the parotid primary. The clinical findings, management, and a review of the current literature are reported. Metastases from PSAs are extraordinary. We describe the first reported metastasis from the parotid to the thyroid gland. In this case, we report an excellent outcome post-operatively and argue for the benefit of long-term follow-up.

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“…Recurrent pleomorphic adenoma is often multifocal, involving both the tumor bed and the adjacent spaces. These lesions, often small nodules with diameter less than one centimeter, appear strongly hyperintense in T2 sequences, which are easy to identify, according to some authors [5]. …”

Section: Discussionmentioning

confidence: 99%

Massive Multinodular Head and Neck Recurrence of Parotid Gland Pleomorphic Adenoma: A Case Report

Philouze

Sigaux

Manichon

et al. 2014

Case Reports in Otolaryngology

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Introduction. The optimal initial management of parotid pleomorphic adenomas reduces the risk of recurrence and malignant transformation. Surgery of recurrence can be difficult in multinodular disseminated forms. Case Report. A 67-years-old patient was referred for management of a large multifocal recurrence of a pleomorphic adenoma operated on 23 years ago. The clinical and radiological assessment found parapharyngeal, infratemporal, and prestyloid invasion, with nodules in the sternocleidomastoid muscle. Excision by transmandibular approach was performed. The pathologist found a multinodular recurrent pleomorphic adenoma without criteria of malignancy. Postoperative radiotherapy was performed. Discussion. Multinodular forms and incomplete resections are the most important factors that are thought to predispose to recurrence. A precise analysis of the extension by preoperative MRI is essential. Adjuvant radiotherapy can be given in these recurrent multifocal forms.

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Imaging Characteristics of Recurrent Pleomorphic Adenoma of the Parotid Gland

Cited by 43 publications

References 32 publications

CD24 and CD44 in salivary gland pleomorphic adenoma and in human salivary gland morphogenesis: differential markers of glandular structure or stem cell indicators?

CD24 and CD44 in salivary gland pleomorphic adenoma and in human salivary gland morphogenesis: differential markers of glandular structure or stem cell indicators?

A unique case of benign pleomorphic adenoma metastasizing to the thyroid gland and liver

Massive Multinodular Head and Neck Recurrence of Parotid Gland Pleomorphic Adenoma: A Case Report

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