Imaging Appearance and Clinical Impact of Preoperative Breast MRI in Pregnancy-Associated Breast Cancer

Myers, Kelly; Green, Lauren; Lebron, Lizza; Morris, Elizabeth A.

doi:10.2214/ajr.16.17124

Cited by 36 publications

(21 citation statements)

References 26 publications

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“…Experience with MRI in pregnancy is limited and gadolinium‐enhanced contrast is contraindicated in the first trimester because it crosses the placenta. A recent study of breast MRI showed 98% sensitivity in diagnosis of pregnancy‐associated breast cancer and changed treatment modality in 28% of women . Comprehensive staging studies are needed because breast cancer in pregnancy may present in advanced stage.…”

Section: Specific Cancersmentioning

confidence: 99%

Cancer in pregnancy

Botha

Rajaram

Karunaratne

2018

Intl J Gynecology & Obste

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The incidence of cancer in pregnancy is increasing. The most frequent malignancies include breast and cervical cancers. Diagnosis may be complicated by late presentation. Imaging during pregnancy should consider risks to the fetus. Diagnostic work‐up, including tumor markers, can be influenced by the physiology of pregnancy. Treatment of cancer can often be safely administered with good maternal and fetal outcomes. Chemotherapy, radiotherapy, and surgery must be adapted to the pregnancy state. Counselling and emotional support are an essential part of management.

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Section: Specific Cancersmentioning

confidence: 99%

Cancer in pregnancy

Botha

Rajaram

Karunaratne

2018

Intl J Gynecology & Obste

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“…Detection rates of PABC are very high using mammography, ultrasonography (US) or magnetic resonance (MRI) being 91%, 100% and 97%, respectively, according to Myers et al [13].…”

Section: Diagnostic Imagingmentioning

confidence: 99%

“…Breast MRI has a sensitivity of 98% [13]. Contrastenhanced MRI is not recommended during the first trimester of pregnancy because the contrast agent used, gadolinium, is classified as pregnancy category C. Gadolinium-based contrast media cross the placenta in measurable quantities and can be identified in the amniotic fluid [22].…”

Section: Diagnostic Imagingmentioning

confidence: 99%

The role of imaging techniques in the diagnosis, staging and choice of therapeutic conduct in pregnancy associated breast cancer

et al. 2019

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Breast cancer diagnosed during pregnancy is at increasing incidence due to the increased frequency of obesity, the postponement of the first pregnancy to later decades of life and the advances of diagnostic techniques. Clinical and imaging diagnosis is difficult during gestation due to adaptive changes of the maternal organism , the mammary glads in particular. Furthermore, the therapeutic approach is limited both by the possible side effects on the fetus and by the skepticism of the couple over these therapeutic regimens.The present paper aims to review the main diagnostic steps to confirm pregnancy associated breast cancer, as well as the therapeutic possibilities during this period, related to the potential adverse effects concerning pregnancy

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“…Pregnancy-associated breast cancer (PABC) is determined as a breast malignancy identified for women during pregnancy or within the first twelve postpartum months (1,2). Some evidence suggests that it is worthwhile to differentiate between diagnosis during pregnancy and diagnosis during the postpartum phase (18) because separating patients in this way reveals a potential prognostic difference between the two groups.…”

Section: Introductionmentioning

confidence: 99%

Imaging in pregnancy-associated breast cancer: a case report

Untanas

Grigaitė

Briedienė

2019

AML

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Background. PABC (pregnancy-associated breast cancer) is a rare condition that appears as a malignancy in 1 per 3000 pregnant women and is one of the most common cancers diagnosed during pregnancy or the postpartum period. If a woman who is pregnant or within a year after delivery has complaints of a palpable breast mass, it could undeniably be a malignant mass of the breast. That is why an ultrasound should be performed for all pregnant or lactating women who detect a palpable breast mass that persists for two or more weeks. Case report. Our case report presents a pregnant 40-year-old previously healthy female at 36 weeks gestational age with a complaint of a palpable left breast mass for two months period. The initial ultrasound showed a breast tumour of irregular shape, solid and hypervascular mass. Conclusions. Early diagnostics of PABC is of crucial importance in order to offer the best possible outcomes for the patient and foetus.

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Imaging Appearance and Clinical Impact of Preoperative Breast MRI in Pregnancy-Associated Breast Cancer

Abstract: Breast MRI had a high sensitivity for PABC in our study population. MRI may play an important role in PABC because it changed the surgical management of 28% of patients.

Cited by 36 publications

References 26 publications

Cancer in pregnancy

Cancer in pregnancy

The role of imaging techniques in the diagnosis, staging and choice of therapeutic conduct in pregnancy associated breast cancer

Imaging in pregnancy-associated breast cancer: a case report

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