The colour appearance of a stimulus is not independent of its spatial and temporal characteristics. The prints in the graphic arts are both colorimetrically and spatially variable surfaces due to the use of halftoning with different inks. The spatial and temporal characteristics of the human visual system are typically explored through the measurement of contrast sensitivity functions. Contrast sensitivity functions (CSFs) in vision science are analogous to modulation transfer functions (MTFs) in imaging science. The contrast sensitivity function (CSF) is essential for the detail perception and it is one of the main components of visual models and metrics. CSF is a well researched but never the less, CSF has not been widely researched in terms of application in hardcopy prints made by digital printing systems, but mainly on colour displays. The aim of this paper was to determine if there is any similarity between two types of reducing contrast: (1) type C1 where two opponent colours get mixed; and (2) type C2 where the colour saturation is reduced. A group of 15 subjects evaluated a printed test form containing frequency and contrast variable elements using magnifying glass.The results showed that the eye is similarly sensitive to both types of the contrast change. The plots of reducing saturation (C2) showed a similar shape like C1 but had slightly lower sensitivity, especially in the red-green contrast. This can be useful for color difference metrics cut-offs and for designers in determining which details and contrasts do not have to be used as they cannot be seen by the final observer.