Abstract:Estimated MITC concentrations during the episode exceeded both the 4-minute NOEL and 1-hourNOELby approximately four fold. The high concentrations of MITC present in the affected neighborhood may have been partially attributable to failure to immediately complete a required post-application water-treatment on 15 of the 100 treated acres. However, because of the limited area involved, the violation was unlikely to have accounted for the entire incident. Similar episodes may occur when metam-sodium fumigants are… Show more
“…Three articles identified from the authors' references were added, leading to a total of 68 articles. Seven papers were excluded after reading the full text of the article: four dealt with overall mortality but did not specifically deal with respiratory diseases [18][19][20][21], two were toxicology studies [22,23] and one investigated idiopathic pulmonary fibrosis without mentioning exposure to pesticides [24]. Thus, 61 articles were finally selected for review ( fig.…”
This article aims to review the available literature regarding the link between occupational exposure to pesticides and respiratory symptoms or diseases. Identification of epidemiological studies was performed using PubMed. 41 articles were included, 36 regarding agricultural workers and five regarding industry workers.Among the 15 cross-sectional studies focusing on respiratory symptoms and agricultural pesticide exposure, 12 found significant associations with chronic cough, wheeze, dyspnoea, breathlessness or chest tightness. All four studies on asthma found a relationship with occupational exposure, as did all three studies on chronic bronchitis. The four studies that performed spirometry reported impaired respiratory function linked to pesticide exposure, suggestive of either obstructive or restrictive syndrome according to the chemical class of pesticide.12 papers reported results from cohort studies. Three out of nine found a significant relationship with increased risk of wheeze, five out of nine with asthma and three out of three with chronic bronchitis. In workers employed in pesticide production, elevated risks of chronic obstructive pulmonary disease (two studies out of three) and impaired respiratory function suggestive of an obstructive syndrome (two studies out of two) were reported.In conclusion, this article suggests that occupational exposure to pesticides is associated with an increased risk of respiratory symptoms, asthma and chronic bronchitis, but the causal relationship is still under debate. @ERSpublications A review of occupational (agricultural and industry) exposure to pesticides and associated respiratory health effects http:///ow.ly/M09Gc
“…Three articles identified from the authors' references were added, leading to a total of 68 articles. Seven papers were excluded after reading the full text of the article: four dealt with overall mortality but did not specifically deal with respiratory diseases [18][19][20][21], two were toxicology studies [22,23] and one investigated idiopathic pulmonary fibrosis without mentioning exposure to pesticides [24]. Thus, 61 articles were finally selected for review ( fig.…”
This article aims to review the available literature regarding the link between occupational exposure to pesticides and respiratory symptoms or diseases. Identification of epidemiological studies was performed using PubMed. 41 articles were included, 36 regarding agricultural workers and five regarding industry workers.Among the 15 cross-sectional studies focusing on respiratory symptoms and agricultural pesticide exposure, 12 found significant associations with chronic cough, wheeze, dyspnoea, breathlessness or chest tightness. All four studies on asthma found a relationship with occupational exposure, as did all three studies on chronic bronchitis. The four studies that performed spirometry reported impaired respiratory function linked to pesticide exposure, suggestive of either obstructive or restrictive syndrome according to the chemical class of pesticide.12 papers reported results from cohort studies. Three out of nine found a significant relationship with increased risk of wheeze, five out of nine with asthma and three out of three with chronic bronchitis. In workers employed in pesticide production, elevated risks of chronic obstructive pulmonary disease (two studies out of three) and impaired respiratory function suggestive of an obstructive syndrome (two studies out of two) were reported.In conclusion, this article suggests that occupational exposure to pesticides is associated with an increased risk of respiratory symptoms, asthma and chronic bronchitis, but the causal relationship is still under debate. @ERSpublications A review of occupational (agricultural and industry) exposure to pesticides and associated respiratory health effects http:///ow.ly/M09Gc
“…Three articles from the authors' references were added to the 65 articles deemed relevant, giving a total of 68 articles. Reading the full text articles led to exclusion of another seven items: four did not specifically deal with respiratory diseases but instead with overall mortality [23][24][25][26], two studies were purely toxicological [27,28] and the last one investigated cases of idiopathic pulmonary fibrosis with no notion about exposure to pesticides [29]. Thus, among the 61 articles finally selected, 41 dealt with occupational exposures and were summarised in another review, and 20 papers studied environmental exposures and are summarised in this review ( fig.…”
Respiratory effects of environmental exposure to pesticides are debated. Here we aimed to review epidemiological studies published up until 2013, using the PubMed database. 20 studies dealing with respiratory health and non-occupational pesticide exposure were identified, 14 carried out on children and six on adults.In four out of nine studies in children with biological measurements, mothers' dichlorodiphenyldichloroethylene (DDE) blood levels during pregnancy were associated with asthma and wheezing in young children. An association was also found between permethrin in indoor air during pregnancy and wheezing in children. A significant association between asthma and DDE measured in children's blood (aged 7-10 years) was observed in one study. However, in three studies, no association was found between asthma or respiratory infections in children and pesticide levels in breast milk and/or infant blood. Lastly, in three out of four studies where post-natal pesticide exposure of children was assessed by parental questionnaire an association with respiratory symptoms was found. Results of the fewer studies on pesticide environmental exposure and respiratory health of adults were much less conclusive: indeed, the associations observed were weak and often not significant.In conclusion, further studies are needed to confirm whether there is a respiratory risk associated with environmental exposure to pesticides. @ERSpublications Occupational pesticide exposure increases respiratory health risk but data are unclear for environmental exposures http://ow.ly/PSGvz
“…Use of the ISC3 model to estimate flux from similar applications has been described previously for air pollution events involving both chloropicrin 4,6 and the metamsodium by-product methyl isothiocyanate (MITC). 3,5 Initial chloropicrin air concentration estimates from the ISC3 model are presented here lbs chloropicrin gallons 2.2lb/kg 1 kg/1,000,000 mg 3.785 . lbs.…”
Section: Application Sourcementioning
confidence: 99%
“…This has been accompanied by multiple illness episodes in areas where treated fields are juxtaposed with housing. [3][4][5][6] …”
Ocular, respiratory, and systemic symptoms on the evening of October 5, 2005, corresponded to a plume of chloropicrin, with estimated concentrations as high as 0.15 ppm, in the community of Salinas, California. Cases occurred between 0.36 and 2.89 miles from the application site. Use of irritant agricultural fumigants near residential neighborhoods can produce a risk of illness for distances more than 2 miles from the site of application. Air modeling is useful for evaluating the relationship between possible exposures and community symptoms.
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