Iliac crest donor site morbidity in foot and ankle surgery

Schulhofer, S. David; Oloff, Lawrence M.

doi:10.1016/s1067-2516(97)80064-6

Cited by 32 publications

(19 citation statements)

References 22 publications

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“…5,6 Additional commonly reported problems include nerve injury, hemorrhage, fracture, and hernia. [25][26][27][28] Due to this significant morbidity, autologous bone grafting …”

Section: Clinical Outcomes Autograftmentioning

confidence: 99%

Perspectives on the clinical utility of allografts for bone regeneration within osseous defects: a narrative review

Miller¹,

Block²

2011

ORR

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A variety of bone grafts and bone graft substitutes is available for treatment of osseous defects although adequate reconstruction of the residual void following fracture, arthroplasty, or tumor/cyst resection remains a therapeutic challenge. This narrative review evaluates the peer-reviewed literature and examines relevant outcomes in patients treated with bone grafts and bone graft substitutes for surgical management of osseous defects. Although autograft, xenograft, and ceramic bone graft substitutes are used for a variety of orthopedic applications, they have distinct limitations in clinical practice. Bone allograft material is a safe and effective adjunct to treatment of osseous defects.

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“…5,6 Additional commonly reported problems include nerve injury, hemorrhage, fracture, and hernia. [25][26][27][28] Due to this significant morbidity, autologous bone grafting …”

Section: Clinical Outcomes Autograftmentioning

confidence: 99%

Perspectives on the clinical utility of allografts for bone regeneration within osseous defects: a narrative review

Miller¹,

Block²

2011

ORR

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“…Autogenous bone is generally considered the gold-standard graft material [18]. The unique advantage of the autograft is that it contains viable osteoblasts and osteogenic precursor cells that can contribute to the formation of new bone [1].…”

Section: Autograftmentioning

confidence: 99%

Potential of an ultraporous ?-tricalcium phosphate synthetic cancellous bone void filler and bone marrow aspirate composite graft

Em¹,

Jg²,

Td³

et al. 2001

European Spine Journal

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“…Autologous bone grafts are currently viewed as the gold standard [1][2][3] , however, they are limited because of the highly invasive, the complications of the donor site, and the high risk of infection. Therefore, research and development into bone substitutes is needed.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of a Porous Hydroxyapatite Granule and Gelatin Hydrogel Microsphere Composite in Bone Regeneration

Yokota

Matsuno

Tabata

et al. 2017

J. Hard Tissue Biology.

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The purpose of this study was to investigate the property of hydroxyapatite (HA)/gelatin hydrogel (GH) composite granules as a scaffold and controlled-release carrier of basic fibroblast growth factor (bFGF) for bone regeneration. HA granules and GH microsphere at various weight ratios to the HA granules were mixed. The composite provided the controlled release of bFGF in vitro. The critical-sized bone defects of 6 mm diameter were created in the skull of New Zealand white rabbits and the composite granules with or without incorporated bFGF, were implanted into the defects. Bone regeneration and were evaluated by computed tomography and H-E staining. The composite granules incorporating bFGF promoted significantly higher bone regeneration at the defect site as compared to the bFGF-free composites. Further, the amount of new bone increased in proportion to the amount of GH microspheres incorporated into the composite. We conclude that the bFGF-impregnated HA/GH composite granules is useful for bone regeneration.

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Iliac crest donor site morbidity in foot and ankle surgery

Cited by 32 publications

References 22 publications

Perspectives on the clinical utility of allografts for bone regeneration within osseous defects: a narrative review

Perspectives on the clinical utility of allografts for bone regeneration within osseous defects: a narrative review

Potential of an ultraporous ?-tricalcium phosphate synthetic cancellous bone void filler and bone marrow aspirate composite graft

Evaluation of a Porous Hydroxyapatite Granule and Gelatin Hydrogel Microsphere Composite in Bone Regeneration

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